Thirty-thousand-year-old distant relative of giant icosahedral DNA viruses with a pandoravirus morphology

…, J Bartoli, L Shmakova, S Jeudy… - Proceedings of the …, 2014 - National Acad Sciences
The largest known DNA viruses infect Acanthamoeba and belong to two markedly different
families. The Megaviridae exhibit pseudo-icosahedral virions up to 0.7 μm in diameter and …

In-depth study of Mollivirus sibericum, a new 30,000-y-old giant virus infecting Acanthamoeba

…, A Lartigue, L Bertaux, S Jeudy… - Proceedings of the …, 2015 - National Acad Sciences
Acanthamoeba species are infected by the largest known DNA viruses. These include
icosahedral Mimiviruses, amphora-shaped Pandoraviruses, and Pithovirus sibericum, the latter …

Genome of Phaeocystis globosa virus PgV-16T highlights the common ancestry of the largest known DNA viruses infecting eukaryotes

S Santini, S Jeudy, J Bartoli, O Poirot… - Proceedings of the …, 2013 - National Acad Sciences
Large dsDNA viruses are involved in the population control of many globally distributed species
of eukaryotic phytoplankton and have a prominent role in bloom termination. The genus …

[HTML][HTML] Escherichia coli ykfE ORFan gene encodes a potent inhibitor of C-type lysozyme

V Monchois, C Abergel, J Sturgis, S Jeudy… - Journal of Biological …, 2001 - ASBMB
The complete nucleotide sequences of over 37 microbial and three eukaryote genomes are
already publicly available, and more sequencing is in progress. Despite this accumulation of …

[HTML][HTML] Diversity and evolution of the emerging Pandoraviridae family

M Legendre, E Fabre, O Poirot, S Jeudy… - Nature …, 2018 - nature.com
With DNA genomes reaching 2.5 Mb packed in particles of bacterium-like shape and
dimension, the first two Acanthamoeba-infecting pandoraviruses remained up to now the most …

[PDF][PDF] Virus-encoded histone doublets are essential and form nucleosome-like structures

Y Liu, H Bisio, CM Toner, S Jeudy, N Philippe, K Zhou… - Cell, 2021 - cell.com
The organization of genomic DNA into defined nucleosomes has long been viewed as a
hallmark of eukaryotes. This paradigm has been challenged by the identification of "minimalist" …

[PDF][PDF] Structural and functional studies of Nup107/Nup133 interaction and its implications for the architecture of the nuclear pore complex

T Boehmer, S Jeudy, IC Berke, TU Schwartz - Molecular cell, 2008 - cell.com
Nuclear pore complexes (NPCs) are 40–60 MDa protein assemblies embedded in the nuclear
envelope of eukaryotic cells. NPCs exclusively mediate all transport between cytoplasm …

[HTML][HTML] Noumeavirus replication relies on a transient remote control of the host nucleus

E Fabre, S Jeudy, S Santini, M Legendre… - Nature …, 2017 - nature.com
Acanthamoeba are infected by a remarkable diversity of large dsDNA viruses, the infectious
cycles of which have been characterized using genomics, transcriptomics and electron …

[HTML][HTML] Evolution of giant pandoravirus revealed by CRISPR/Cas9

…, C Giry, N Philippe, JM Alempic, S Jeudy… - Nature …, 2023 - nature.com
Giant viruses (GVs) are a hotspot of unresolved controversies since their discovery, including
the definition of “Virus” and their origin. While increasing knowledge of genome diversity …

[HTML][HTML] The DNA methylation landscape of giant viruses

S Jeudy, S Rigou, JM Alempic, JM Claverie… - Nature …, 2020 - nature.com
DNA methylation is an important epigenetic mark that contributes to various regulations in
all domains of life. Giant viruses are widespread dsDNA viruses with gene contents …