[HTML][HTML] A flexible network of vimentin intermediate filaments promotes migration of amoeboid cancer cells through confined environments

SB Lavenus, SM Tudor, MF Ullo, KW Vosatka… - Journal of Biological …, 2020 - ASBMB
Tumor cells can spread to distant sites through their ability to switch between mesenchymal
and amoeboid (bleb-based) migration. Because of this difference, inhibitors of metastasis …

Emerin regulation of nuclear stiffness is required for fast amoeboid migration in confined environments

SB Lavenus, KW Vosatka, AP Caruso… - Journal of Cell …, 2022 - journals.biologists.com
When metastasizing, tumor cells must traverse environments with diverse physicochemical
properties. Recently, the cell nucleus has emerged as a major regulator of the transition from …

[HTML][HTML] A novel Fiji/ImageJ plugin for the rapid analysis of blebbing cells

KW Vosatka, SB Lavenus, JS Logue - PloS one, 2022 - journals.plos.org
When confined, cells have recently been shown to undergo a phenotypic switch to what has
been termed, fast amoeboid (leader bleb-based) migration. However, as this is a nascent …

[HTML][HTML] The amoeboid migration of monocytes in confining channels requires the local remodeling of the cortical actin cytoskeleton by cofilin-1

MF Ullo, AE D'Amico, SB Lavenus, JS Logue - Research Square, 2023 - ncbi.nlm.nih.gov
Within the bloodstream, monocytes must traverse the microvasculature to prevent leukostasis,
which is the entrapment of monocytes within the confines of the microvasculature. Using …

A flexible network of Vimentin intermediate filaments promotes the migration of amoeboid cancer cells through confined environments

SM Tudor, SB Lavenus, JS Logue - bioRxiv, 2019 - biorxiv.org
The spread of tumor cells to distant sites is promoted by their ability to switch between
mesenchymal and amoeboid (bleb-based) migration. Because of this, inhibitors of metastasis …

Emerin regulation of nuclear stiffness is required for the amoeboid migration of cancer cells in confining environments

SB Lavenus, KW Vosatka, MF Ullo, JS Logue - bioRxiv, 2020 - biorxiv.org
Through the process of regulating cell deformability in confined environments, the nucleus
has emerged as a major regulator of cell migration. Here, we demonstrate that nuclear …

[PDF][PDF] A novel Fiji/ImageJ-based macro identifies the limitations of F-actin markers in studying the fast amoeboid migration of confined cells

KW Vosatka, SB Lavenus, JS Logue - scholar.archive.org
When confined, cells have recently been shown to undergo a phenotypic switch to what has
been termed, fast amoeboid (leader bleb-based) migration. However, as this is a nascent …

Behaviour of mesenchymal stem cells, fibroblasts and osteoblasts on smooth surfaces

S Lavenus, P Pilet, J Guicheux, P Weiss, G Louarn… - Acta biomaterialia, 2011 - Elsevier
Understanding of the interactions between cells and surfaces is essential in the field of tissue
engineering and biomaterials. This study aimed to compare the adhesion, proliferation and …

Label-free cell signaling pathway deconvolution of angiotensin type 1 receptor reveals time-resolved G-protein activity and distinct AngII and AngIIIIV responses

S Lavenus, É Simard, É Besserer-Offroy… - Pharmacological …, 2018 - Elsevier
Sandrine Lavenus a b 1 , Élie Simard a b 1 , Élie Besserer-Offroy a b , Ulrike Froehlich a b ,
Richard Leduc a b … (B) Amplitudes of the reflection variations for phase I and (C) amplitudes …

Cell-penetrating pepducins targeting the neurotensin receptor type 1 relieve pain

…, CE Mona, M Chartier, S Lavenus… - Pharmacological …, 2020 - Elsevier
… 1A and B, we show G protein activation for each condition 15 min post-stimulation. We
observed partial Gα q protein activation by the pepducins PP-001 to PP-005, ranging in …