Metabolic regulation of gene expression by histone lactylation
The Warburg effect, which originally described increased production of lactate in cancer, is
associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of …
associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of …
Reversible protein inactivation by optogenetic trapping in cells
We present a versatile platform to inactivate proteins in living cells using light, light-activated
reversible inhibition by assembled trap (LARIAT), which sequesters target proteins into …
reversible inhibition by assembled trap (LARIAT), which sequesters target proteins into …
Optogenetic control of endogenous Ca2+ channels in vivo
Calcium (Ca 2+ ) signals that are precisely modulated in space and time mediate a myriad of
cellular processes, including contraction, excitation, growth, differentiation and apoptosis 1 …
cellular processes, including contraction, excitation, growth, differentiation and apoptosis 1 …
[HTML][HTML] Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification
We report the identification of 67 previously undescribed histone modifications, increasing
the current number of known histone marks by about 70%. We further investigated one of the …
the current number of known histone marks by about 70%. We further investigated one of the …
[HTML][HTML] Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ
Brown adipose tissue (BAT) can disperse stored energy as heat. Promoting BAT-like features
in white adipose (WAT) is an attractive, if elusive, therapeutic approach to staunch the …
in white adipose (WAT) is an attractive, if elusive, therapeutic approach to staunch the …
[PDF][PDF] Metabolic regulation of gene expression by histone lysine β-hydroxybutyrylation
…, M Kirkey, D Wang, LM Jensen, OK Kwon, S Lee… - Molecular cell, 2016 - cell.com
Here we report the identification and verification of a β-hydroxybutyrate-derived protein
modification, lysine β-hydroxybutyrylation (Kbhb), as a new type of histone mark. Histone Kbhb …
modification, lysine β-hydroxybutyrylation (Kbhb), as a new type of histone mark. Histone Kbhb …
Tissue-like skin-device interface for wearable bioelectronics by using ultrasoft, mass-permeable, and low-impedance hydrogels
Hydrogels consist of a cross-linked porous polymer network and water molecules occupying
the interspace between the polymer chains. Therefore, hydrogels are soft and moisturized, …
the interspace between the polymer chains. Therefore, hydrogels are soft and moisturized, …
Aqueous processing of natural graphite particulates for lithium-ion battery anodes and their electrochemical performance
Aqueous-based natural graphite particulates for fabrication of lithium-ion battery anodes are
investigated with emphasis on chemical control of suspension component interactions …
investigated with emphasis on chemical control of suspension component interactions …
Wearable and implantable soft bioelectronics: device designs and material strategies
High-performance wearable and implantable devices capable of recording physiological
signals and delivering appropriate therapeutics in real time are playing a pivotal role in …
signals and delivering appropriate therapeutics in real time are playing a pivotal role in …
Smart contact lenses with graphene coating for electromagnetic interference shielding and dehydration protection
Recently, smart contact lenses with electronic circuits have been proposed for various
sensor and display applications where the use of flexible and biologically stable electrode …
sensor and display applications where the use of flexible and biologically stable electrode …