User profiles for Sangkyu Lee

Sangkyu Lee

- Verified email at skku.edu - Cited by 7264

Sangkyu Lee

- Verified email at snu.ac.kr - Cited by 2145

Sangkyu Lee

- Verified email at ibs.re.kr - Cited by 1311

Metabolic regulation of gene expression by histone lactylation

…, H Huang, G Zhou, C Cui, Y Weng, W Liu, S Kim, S Lee… - Nature, 2019 - nature.com
The Warburg effect, which originally described increased production of lactate in cancer, is
associated with diverse cellular processes such as angiogenesis, hypoxia, polarization of …

Reversible protein inactivation by optogenetic trapping in cells

S Lee, H Park, T Kyung, NY Kim, S Kim, J Kim… - Nature …, 2014 - nature.com
We present a versatile platform to inactivate proteins in living cells using light, light-activated
reversible inhibition by assembled trap (LARIAT), which sequesters target proteins into …

Optogenetic control of endogenous Ca2+ channels in vivo

T Kyung, S Lee, JE Kim, T Cho, H Park, YM Jeong… - Nature …, 2015 - nature.com
Calcium (Ca 2+ ) signals that are precisely modulated in space and time mediate a myriad of
cellular processes, including contraction, excitation, growth, differentiation and apoptosis 1 …

[HTML][HTML] Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

M Tan, H Luo, S Lee, F Jin, JS Yang, E Montellier… - Cell, 2011 - cell.com
We report the identification of 67 previously undescribed histone modifications, increasing
the current number of known histone marks by about 70%. We further investigated one of the …

[HTML][HTML] Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ

L Qiang, L Wang, N Kon, W Zhao, S Lee, Y Zhang… - Cell, 2012 - cell.com
Brown adipose tissue (BAT) can disperse stored energy as heat. Promoting BAT-like features
in white adipose (WAT) is an attractive, if elusive, therapeutic approach to staunch the …

[PDF][PDF] Metabolic regulation of gene expression by histone lysine β-hydroxybutyrylation

…, M Kirkey, D Wang, LM Jensen, OK Kwon, S Lee… - Molecular cell, 2016 - cell.com
Here we report the identification and verification of a β-hydroxybutyrate-derived protein
modification, lysine β-hydroxybutyrylation (Kbhb), as a new type of histone mark. Histone Kbhb …

Tissue-like skin-device interface for wearable bioelectronics by using ultrasoft, mass-permeable, and low-impedance hydrogels

…, S Baik, OK Park, SH Choi, T Hyeon, JH Kim, S Lee… - Science …, 2021 - science.org
Hydrogels consist of a cross-linked porous polymer network and water molecules occupying
the interspace between the polymer chains. Therefore, hydrogels are soft and moisturized, …

Aqueous processing of natural graphite particulates for lithium-ion battery anodes and their electrochemical performance

JH Lee, S Lee, U Paik, YM Choi - Journal of power sources, 2005 - Elsevier
Aqueous-based natural graphite particulates for fabrication of lithium-ion battery anodes are
investigated with emphasis on chemical control of suspension component interactions …

Wearable and implantable soft bioelectronics: device designs and material strategies

SH Sunwoo, KH Ha, S Lee, N Lu… - Annual review of …, 2021 - annualreviews.org
High-performance wearable and implantable devices capable of recording physiological
signals and delivering appropriate therapeutics in real time are playing a pivotal role in …

Smart contact lenses with graphene coating for electromagnetic interference shielding and dehydration protection

S Lee, I Jo, S Kang, B Jang, J Moon, JB Park, S Lee… - ACS …, 2017 - ACS Publications
Recently, smart contact lenses with electronic circuits have been proposed for various
sensor and display applications where the use of flexible and biologically stable electrode …