User profiles for Sanne Hertegonne
 | Sanne HertegonnePhD candidate, University of Zürich Verified email at usz.ch Cited by 84 |
[HTML][HTML] Hyperinflammatory environment drives dysfunctional myeloid cell effector response to bacterial challenge in COVID-19
…, DA Hofmaenner, TC Scheier, S Hertegonne… - PLoS …, 2022 - journals.plos.org
COVID-19 displays diverse disease severities and symptoms including acute systemic
inflammation and hypercytokinemia, with subsequent dysregulation of immune cells. Bacterial …
inflammation and hypercytokinemia, with subsequent dysregulation of immune cells. Bacterial …
[HTML][HTML] Neutrophils dominate in opsonic phagocytosis of P. falciparum blood-stage merozoites and protect against febrile malaria
…, S Singh, MK Das, MH Dziegiel, S Hertegonne… - Communications …, 2021 - nature.com
Antibody-mediated opsonic phagocytosis (OP) of Plasmodium falciparum blood-stage
merozoites has been associated with protection against malaria. However, the precise …
merozoites has been associated with protection against malaria. However, the precise …
Blunted sFasL signalling exacerbates TNF‐driven neutrophil necroptosis in critically ill COVID‐19 patients
…, CC Chang, J Baum, S Hertegonne… - Clinical & …, 2021 - Wiley Online Library
Objectives Critically ill coronavirus disease 2019 (COVID‐19) patients are characterised by
a severely dysregulated cytokine profile and elevated neutrophil counts, impacting disease …
a severely dysregulated cytokine profile and elevated neutrophil counts, impacting disease …
C-di-AMP levels modulate Staphylococcus aureus cell wall thickness, response to oxidative stress, and antibiotic resistance and tolerance
…, J Bär, M von Matt, S Hertegonne… - Microbiology …, 2023 - Am Soc Microbiol
Beta-lactam antibiotics are widely used to treat infections caused by the important human
pathogen Staphylococcus aureus. Resistance to beta-lactams, as found in methicillin-resistant …
pathogen Staphylococcus aureus. Resistance to beta-lactams, as found in methicillin-resistant …
Serine-threonine phosphoregulation by PknB and Stp contributes to quiescence and antibiotic tolerance in Staphylococcus aureus
Staphylococcus aureus can cause infections that are often chronic and difficult to treat, even
when the bacteria are not antibiotic resistant because most antibiotics act only on …
when the bacteria are not antibiotic resistant because most antibiotics act only on …
Group A Streptococcus strains causing meningitis without distinct invasive phenotype
Group A streptococcal (GAS; aka Streptococcus pyogenes) meningitis is a fulminant disease
associated with high morbidity and mortality. To elucidate the mechanisms underlying the …
associated with high morbidity and mortality. To elucidate the mechanisms underlying the …
Antibacterial Neutrophil Effector Response: Ex Vivo Quantification of Regulated Cell Death Associated with Extracellular Trap Release
Regulated cell death (RCD) and the concomitant release of extracellular traps by neutrophils
(NETs) constitute an important antibacterial effector response. Usually, the dynamic …
(NETs) constitute an important antibacterial effector response. Usually, the dynamic …
Blunted Fas signaling favors RIPK1-driven neutrophil necroptosis in critically ill COVID-19 patients
Critically ill COVID-19 patients are characterized by a severely dysregulated cytokine profile
and elevated neutrophil counts, which are thought to contribute to disease severity. However…
and elevated neutrophil counts, which are thought to contribute to disease severity. However…
[PDF][PDF] Blunted sFasL signalling exacerbates TNF-driven neutrophil necroptosis in critically ill COVID-19 patients
S Hertegonne, E Hitz, TC Scheier, DA Hofmaenner… - 2021 - scholar.archive.org
Objectives Critically ill coronavirus disease 2019 (COVID-19) patients are characterised by
a severely dysregulated cytokine profile and elevated neutrophil counts, impacting disease …
a severely dysregulated cytokine profile and elevated neutrophil counts, impacting disease …
Blunted Fas signaling favors RIPK1-driven neutrophil necroptosis in critically ill COVID-19 patients (preprint)
Critically ill COVID-19 patients are characterized by a severely dysregulated cytokine profile
and elevated neutrophil counts, which are thought to contribute to disease severity. However…
and elevated neutrophil counts, which are thought to contribute to disease severity. However…