User profiles for Sanoji Wijenayake

Sanoji Wijenayake (Ph.D.)

Assistant Professor - The University of Winnipeg
Verified email at uwinnipeg.ca
Cited by 405

Maternal effects in mammals: broadening our understanding of offspring programming

…, SG Lavergne, LK McCaw, S Wijenayake… - Frontiers in …, 2021 - Elsevier
The perinatal period is a sensitive time in mammalian development that can have long-lasting
consequences on offspring phenotype via maternal effects. Maternal effects have been …

[HTML][HTML] Comparison of methods for pre-processing, exosome isolation, and RNA extraction in unpasteurized bovine and human milk

S Wijenayake, S Eisha, Z Tawhidi, MA Pitino… - PloS one, 2021 - journals.plos.org
Milk is a highly complex, heterogeneous biological fluid that contains non-nutritive, bioactive
extracellular vesicles called exosomes. Characterization of milk-derived exosomes (MDEs) …

The contributions of parental lactation on offspring development: It's not udder nonsense!

S Wijenayake, J Martz, HE Lapp, JA Storm… - Hormones and …, 2023 - Elsevier
The Developmental Origins of Health and Disease (DOHaD) hypothesis describes how
maternal stress exposures experienced during critical periods of perinatal life are linked to …

[HTML][HTML] Maternal high-fat diet induces sex-specific changes to glucocorticoid and inflammatory signaling in response to corticosterone and lipopolysaccharide …

S Wijenayake, MF Rahman, CMW Lum… - Journal of …, 2020 - Springer
Background Maternal obesity as a result of high levels of saturated fat (HFD) consumption
leads to significant negative health outcomes in both mother and exposed offspring. Offspring …

Non-nutritive bioactive components in maternal milk and offspring development: a scoping review

S Eisha, I Joarder, S Wijenayake… - … Origins of Health and …, 2022 - cambridge.org
Lactation is a critical time in mammalian development, where maternal factors shape
offspring outcomes. In this scoping review, we discuss current literature concerning maternal …

Are the effects of catch-and-release angling evident in changes to mRNA abundances related to metabolism, acid–base regulation and stress in lake trout (Salvelinus …

…, KM Jeffries, SJ Cooke, S Wijenayake… - Conservation …, 2023 - academic.oup.com
Catch-and-release (C&R) angling is a conservation-oriented practice intended to reduce
the impact recreational angling has on fish populations. Even though most recreationally …

[HTML][HTML] Anti-apoptotic response during anoxia and recovery in a freeze-tolerant wood frog (Rana sylvatica)

VEM Gerber, S Wijenayake, KB Storey - PeerJ, 2016 - peerj.com
The common wood frog, Rana sylvatica, utilizes freeze tolerance as a means of winter
survival. Concealed beneath a layer of leaf litter and blanketed by snow, these frogs withstand …

The role of DNA methylation during anoxia tolerance in a freshwater turtle (Trachemys scripta elegans)

S Wijenayake, KB Storey - Journal of Comparative Physiology B, 2016 - Springer
Oxygen deprivation is a lethal stress that only a few animals can tolerate for extended
periods. This study focuses on analyzing the role of DNA methylation in aiding natural anoxia …

Dynamic regulation of six histone H3 lysine (K) methyltransferases in response to prolonged anoxia exposure in a freshwater turtle

S Wijenayake, LJ Hawkins, KB Storey - Gene, 2018 - Elsevier
The importance of histone lysine methylation is well established in health, disease, early
development, aging, and cancer. However, the potential role of histone H3 methylation in …

Regulation of pyruvate dehydrogenase (PDH) in the hibernating ground squirrel,(Ictidomys tridecemlineatus)

S Wijenayake, SN Tessier, KB Storey - Journal of Thermal Biology, 2017 - Elsevier
Pyruvate dehydrogenase (PDH) is a vital regulatory enzyme that catalyzes the conversion
of pyruvate into acetyl-CoA and connects anaerobic glycolysis to aerobic TCA cycle. Post-…