User profiles for Santeri Puranen
Santeri PuranenSenior Researcher & Software Developer Verified email at utu.fi Cited by 1417 |
The collagen receptor subfamily of the integrins
The four collagen receptor integrins, α1β1, α2β1, α10β1 and α11β1, form a structurally and
functionally distinct subgroup when compared to other members of the integrin family. In this …
functionally distinct subgroup when compared to other members of the integrin family. In this …
Plasmids shaped the recent emergence of the major nosocomial pathogen Enterococcus faecium
Enterococcus faecium is a gut commensal of humans and animals but is also listed on the
WHO global priority list of multidrug-resistant pathogens. Many of its antibiotic resistance traits …
WHO global priority list of multidrug-resistant pathogens. Many of its antibiotic resistance traits …
[HTML][HTML] Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis
Recent advances in the scale and diversity of population genomic datasets for bacteria now
provide the potential for genome-wide patterns of co-evolution to be studied at the resolution …
provide the potential for genome-wide patterns of co-evolution to be studied at the resolution …
[HTML][HTML] Emergence of ceftazidime-avibactam-resistant Klebsiella pneumoniae during treatment, Finland, December 2018
K Räisänen, I Koivula, H Ilmavirta, S Puranen… - …, 2019 - eurosurveillance.org
In December 2018, a ceftazidime-avibactam (CAZ-AVI)-resistant KPC-2-producing Klebsiella
pneumoniae strain was isolated in Finland. CAZ-AVI resistance was observed 34 days …
pneumoniae strain was isolated in Finland. CAZ-AVI resistance was observed 34 days …
Genome-wide epistasis and co-selection study using mutual information
Covariance-based discovery of polymorphisms under co-selective pressure or epistasis has
received considerable recent attention in population genomics. Both statistical modeling of …
received considerable recent attention in population genomics. Both statistical modeling of …
SuperDCA for genome-wide epistasis analysis
The potential for genome-wide modelling of epistasis has recently surfaced given the
possibility of sequencing densely sampled populations and the emerging families of statistical …
possibility of sequencing densely sampled populations and the emerging families of statistical …
ShaEP: molecular overlay based on shape and electrostatic potential
MJ Vainio, JS Puranen, MS Johnson - 2009 - ACS Publications
ShaEP is a tool for rigid-body superimposition and similarity evaluation of ligand-sized
molecules. Molecular overlay methods traditionally work on either substructures, molecular …
molecules. Molecular overlay methods traditionally work on either substructures, molecular …
[HTML][HTML] α11β1 integrin recognizes the GFOGER sequence in interstitial collagens
WM Zhang, J Käpylä, JS Puranen, CG Knight… - Journal of Biological …, 2003 - ASBMB
The integrins α 1 β 1 , α 2 β 1 , α 10 β 1 , and α 11 β 1 are referred to as a collagen receptor
subgroup of the integrin family. Recently, both α 1 β 1 and α 2 β 1 integrins have been shown …
subgroup of the integrin family. Recently, both α 1 β 1 and α 2 β 1 integrins have been shown …
Genomic rearrangements uncovered by genome-wide co-evolution analysis of a major nosocomial pathogen, Enterococcus faecium
…, AC Schürch, S Puranen… - Microbial …, 2020 - microbiologyresearch.org
Enterococcus faecium is a gut commensal of the gastro-digestive tract, but also known as
nosocomial pathogen among hospitalized patients. Population genetics based on whole-…
nosocomial pathogen among hospitalized patients. Population genetics based on whole-…
Accurate conformation‐dependent molecular electrostatic potentials for high‐throughput in silico drug discovery
JS Puranen, MJ Vainio… - Journal of computational …, 2010 - Wiley Online Library
The atom‐centered partial charges‐approximation is commonly used in current molecular
modeling tools as a computationally inexpensive alternative to quantum mechanics for …
modeling tools as a computationally inexpensive alternative to quantum mechanics for …