Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway
TTH Dinh, H Iseki, S Mizuno, S Iijima-Mizuno… - Elife, 2021 - elifesciences.org
In vivo function of CDK5 and Abl enzyme substrate 2 (Cables2), belonging to the Cables
protein family, is unknown. Here, we found that targeted disruption of the entire Cables2 locus (…
protein family, is unknown. Here, we found that targeted disruption of the entire Cables2 locus (…
Cables2 is a novel Smad2-regulatory factor essential for early embryonic development in mice
TTH Dinh, H Iseki, S Mizuno, S Iijima-Mizuno… - bioRxiv, 2019 - biorxiv.org
CDK5 and Abl enzyme substrate 2 (Cables2), a member of the Cables family that has a C-terminal
cyclin box-like domain, is widely expressed in adult mouse tissues. However, the …
cyclin box-like domain, is widely expressed in adult mouse tissues. However, the …