[HTML][HTML] Diagnosis of Human Leptospirosis in a Clinical Setting: Real-Time PCR High Resolution Melting Analysis for Detection of Leptospira at the Onset of Disease
LM Esteves, SM Bulhões, CC Branco, T Carreira… - Scientific reports, 2018 - nature.com
Currently, direct detection of Leptospira can be done in clinical laboratories by conventional
and by real-time PCR (qRT-PCR). We tested a biobank of paired samples of serum and …
and by real-time PCR (qRT-PCR). We tested a biobank of paired samples of serum and …
[HTML][HTML] Human leptospirosis: seroreactivity and genetic susceptibility in the population of Sao Miguel Island (Azores, Portugal)
LM Esteves, SM Bulhões, CC Branco, FM Mota… - PLoS …, 2014 - journals.plos.org
Background Leptospirosis is a worldwide zoonotic and recognized neglected infectious
disease. It has been observed that only a proportion of individuals exposed to pathogenic …
disease. It has been observed that only a proportion of individuals exposed to pathogenic …
[HTML][HTML] Three multiplex snapshot assays for SNP genotyping in candidate innate immune genes
LM Esteves, SM Bulhões, MJ Brilhante… - BMC research …, 2013 - Springer
Background Innate immune system is the first line of research when studying immune
response to diverse infections and autoimmune/inflammatory diseases. This immune response …
response to diverse infections and autoimmune/inflammatory diseases. This immune response …
Diagnosis of Human Leptospirosis: High Resolution Melting Analysis for Direct Detection of Leptospira in the Early Stage of the Disease in a Clinical Setting
LM Esteves, SM Bulhões, CC Branco, T Carreira… - bioRxiv, 2018 - biorxiv.org
Currently, the direct detection of Leptospira infection can be done in clinical laboratories by
a conventional nested polymerase chain reaction method (nested PCR), which is labourious …
a conventional nested polymerase chain reaction method (nested PCR), which is labourious …
[PDF][PDF] Human Leptospirosis: Seroreactivity and Genetic Susceptibility in the Population of
LM Esteves, SM Bulhoes, CC Branco, FM Mota… - 2014 - academia.edu
Background: Leptospirosis is a worldwide zoonotic and recognized neglected infectious
disease. It has been observed that only a proportion of individuals exposed to pathogenic …
disease. It has been observed that only a proportion of individuals exposed to pathogenic …
[HTML][HTML] A quantitative PCR (TaqMan) assay for pathogenic Leptospira spp
LD Smythe, IL Smith, GA Smith, MF Dohnt… - BMC infectious …, 2002 - Springer
Background Leptospirosis is an emerging infectious disease. The differential diagnosis of
leptospirosis is difficult due to the varied and often "flu like" symptoms which may result in a …
leptospirosis is difficult due to the varied and often "flu like" symptoms which may result in a …
[HTML][HTML] Molecular detection and speciation of pathogenic Leptospiraspp. in blood from patients with culture-negative leptospirosis
S Boonsilp, J Thaipadungpanit, P Amornchai… - BMC infectious …, 2011 - Springer
Background Pathogenic Leptospira spp. present in the blood of patients with leptospirosis
during the first week of symptoms can be detected using culture or PCR. A proportion of …
during the first week of symptoms can be detected using culture or PCR. A proportion of …
Molecular diagnosis of infectious diseases in São Miguel Island (Azores, Portugal): A hospital-based descriptive study
…, T Pereirinha, MJ Brilhante, S Bulhões… - The Journal of Infection …, 2016 - jidc.org
Introduction: We performed a descriptive analysis of molecular diagnosis of infectious
agents in the São Miguel Island population, in order to address questions like what is the …
agents in the São Miguel Island population, in order to address questions like what is the …
[HTML][HTML] Carriers of the Complex Allele HFE c.[187C>G;340+4T>C] Have Increased Risk of Iron Overload in São Miguel Island Population (Azores, Portugal)
CC Branco, CT Gomes, L De Fez, S Bulhões… - Plos one, 2015 - journals.plos.org
Iron overload is associated with acquired and genetic conditions, the most common being
hereditary hemochromatosis (HH) type-I, caused by HFE mutations. Here, we conducted a …
hereditary hemochromatosis (HH) type-I, caused by HFE mutations. Here, we conducted a …
Influenza severe cases in hospitals, between 2014 and 2016 in Portugal
…, J Duarte, T Pereirinha, S Bulhões… - IX Options for the …, 2016 - repositorio.insa.pt
Background: Since 2009, the Portuguese Laboratory Network (PLNID) for Influenza Diagnosis
has integrated 15 Laboratories in mainland and Atlantic Islands of Azores and Madeira. …
has integrated 15 Laboratories in mainland and Atlantic Islands of Azores and Madeira. …