10.7554/eLife.20552.001 Serotonin is implicated in mood and affective disorders. However,
growing evidence suggests that a core endogenous role is to promote flexible adaptation to …

A large body of evidence has indicated that the phasic responses of midbrain dopamine
neurons show a remarkable similarity to a type of teaching signal (temporal difference (TD) error…

The basal ganglia, and the striatum in particular, have been implicated in the generation of
contraversive movements. The striatum projects to downstream basal ganglia nuclei through …

Learning about rewards and punishments is critical for survival. Classical studies have
demonstrated an impressive correspondence between the firing of dopamine neurons in the …

The design of modern scientific experiments requires the control and monitoring of many
different data streams. However, the serial execution of programming instructions in a computer …

The inhibition of sensory responsivity is considered a core serotonin function, yet this
hypothesis lacks direct support due to methodological obstacles. We adapted an optogenetic …

OBJECTIVE: The aim of this paper is to apply an informatics tool for dealing with a medical
decision aiding problem to help infertile couples to become parents, when using assisted …

In the present work, power generation and substrate removal efficiencies of long-term operated
microbial fuel cells, containing abiotic cathodes and biocathodes, were evaluated for 220 …

The electrochemical features of microbial fuel cells’ biocathodes, running on wastewater,
were evaluated by cyclic voltammetry. Ex situ and in situ electrochemical assays were …

Optogenetic methods are now widespread in neuroscience research. Here we present a
detailed surgical procedure to inject adeno-associated viruses and implant optic fiber cannulas …