User profiles for Sara Nakielny

Sara Nakielny

Research Specialist, University of California, San Francisco
Verified email at derisilab.ucsf.edu
Cited by 8374

[PDF][PDF] Transport of proteins and RNAs in and out of the nucleus

S Nakielny, G Dreyfuss - Cell, 1999 - cell.com
Sara Nakielny and Gideon Dreyfuss* Howard Hughes Medical Institute and Department of
Biochemistry and Biophysics University of Pennsylvania School of Medicine tors by the …

Cohabiting family members share microbiota with one another and with their dogs

…, JG Caporaso, D Knights, JC Clemente, S Nakielny… - elife, 2013 - elifesciences.org
10.7554/eLife.00458.001 Human-associated microbial communities vary across individuals:
possible contributing factors include (genetic) relatedness, diet, and age. However, our …

Activation of the MAP kinase pathway by the protein kinase raf

LR Howe, SJ Leevers, N Gómez, S Nakielny, P Cohen… - Cell, 1992 - cell.com
Both MAP kinases and the protein kinase~ 74”“’are activated by many growth factors in a c-ras-dependent
manner and by oncogenic p21’**. We were therefore interested in …

[HTML][HTML] A novel receptor-mediated nuclear protein import pathway

VW Pollard, WM Michael, S Nakielny, MC Siomi… - Cell, 1996 - cell.com
Targeting of most nuclear proteins to the cell nucleus is initiated by interaction between the
classical nuclear localization signals (NLSs) contained within them and the importin NLS …

Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications

…, BA Methé, F Meyer, B Muegge, S Nakielny… - Nature …, 2011 - nature.com
Here we present a standard developed by the Genomic Standards Consortium (GSC) for
reporting marker gene sequences—the minimum information about a marker gene sequence (…

The molecular mechanism by which insulin stimulates glycogen synthesis in mammalian skeletal muscle

P Dent, A Lavoinne, S Nakielny, FB Caudwell, P Watt… - Nature, 1990 - nature.com
The ability of insulin to promote the phosphoryl-ation of some proteins and the dephosphorylation
of others is paradoxical. An insulin-stimulated protein kinase is shown to activate the …

The hnRNP C proteins contain a nuclear retention sequence that can override nuclear export signals.

S Nakielny, G Dreyfuss - The Journal of cell biology, 1996 - rupress.org
Nascent pre-mRNAs associate with the abundant heterogeneous nuclear RNP (hnRNP)
proteins and remain associated with them throughout the time they are in the nucleus. The …

[HTML][HTML] Nup153 is an M9-containing mobile nucleoporin with a novel Ran-binding domain

S Nakielny, S Shaikh, B Burke, G Dreyfuss - The EMBO Journal, 1999 - embopress.org
We employed a phage display system to search for proteins that interact with transportin 1 (TRN1),
the import receptor for shuttling hnRNP proteins with an M9 nuclear localization …

[HTML][HTML] Components of the DNA methylation system of chromatin control are RNA-binding proteins

L Jeffery, S Nakielny - Journal of Biological Chemistry, 2004 - ASBMB
The view that autosomal gene expression is controlled exclusively by protein trans-acting
factors has been challenged recently by the identification of RNA molecules that regulate …

[HTML][HTML] Nuclear export of proteins and RNAs

S Nakielny, G Dreyfuss - Current opinion in cell biology, 1997 - Elsevier
Our understanding of protein export from the nucleus to the cytoplasm has been advanced
recently by the discovery of active, signal-mediated export pathways. Nuclear export signals …