Colony stimulating factor 3 receptor (CSF3R) mutations lead to JAK pathway activation and
are the molecular hallmark of chronic neutrophilic leukemia (CNL). Approximately half of …

Acute myeloid leukemia (AML) is a deadly hematologic malignancy with poor prognosis,
particularly in the elderly. Even among individuals with favorable-risk disease, approximately …

Human exposure to naphthalene (NA), an acute lung toxicant and possible human carcinogen,
is primarily through inhalation. Acute lung toxicity and carcinogenesis are thought to be …

Acute Myeloid Leukemia (AML) develops due to the acquisition of mutations from multiple
functional classes. Here, we demonstrate that activating mutations in the granulocyte colony …

Mutations in SET-binding protein 1 (SETBP1) are associated with poor outcomes in myeloid
leukemias. In the Ras-driven leukemia, juvenile myelomonocytic leukemia, SETBP1 …

In the past few decades, the frequency and severity of wildfires in California has increased.
The majority of studies on wildfire-related human health effects have focused on the criteria …

Naphthalene (NA) is a ubiquitous environmental pollutant and possible human carcinogen
that forms tumors in rodents with tissue/regional and species selectivity. This study seeks to …

Acute myeloid leukemia (AML) is a deadly blood cancer characterized by an overproduction
of immature myeloid cells. AML has a high degree of genetic diversity, and the presence or …

Naphthalene (NA) is a respiratory toxicant and possible human carcinogen. NA is a
ubiquitous combustion product and significant component of jet fuel. The National Toxicology …

Ambient ultrafine particulate matter (UPM), less than 100 nm in size, has been linked to the
development and exacerbation of pulmonary diseases. Age differences in susceptibility to …