Correlation between 3790 quantitative polymerase chain reaction–positives samples and positive cell cultures, including 1941 severe acute respiratory syndrome …

R Jaafar, S Aherfi, N Wurtz, C Grimaldier… - Clinical Infectious …, 2021 - academic.oup.com
RT-PCR for 179 151 patients, of whom 13 161 (7.3%) tested positive. Up to the end of May,
3790 of these samples, reported as positive on nasopharyngeal samples, were inoculated …

[HTML][HTML] Giant viruses of amoebas: an update

S Aherfi, P Colson, B La Scola, D Raoult - Frontiers in microbiology, 2016 - frontiersin.org
During the 12 past years, five new or putative virus families encompassing several members,
namely Mimiviridae, Marseilleviridae, pandoraviruses, faustoviruses, and virophages were …

[HTML][HTML] Choosing a cellular model to study SARS-CoV-2

…, C Boschi, N Wurtz, P Colson, S Aherfi… - Frontiers in Cellular …, 2022 - frontiersin.org
As new pathogens emerge, new challenges must be faced. This is no different in infectious
disease research, where identifying the best tools available in laboratories to conduct an …

[HTML][HTML] Cedratvirus, a double-cork structured giant virus, is a distant relative of pithoviruses

J Andreani, S Aherfi, JY Bou Khalil, F Di Pinto, I Bitam… - Viruses, 2016 - mdpi.com
Most viruses are known for the ability to cause symptomatic diseases in humans and other
animals. The discovery of Acanthamoeba polyphaga mimivirus and other giant amoebal …

[HTML][HTML] Observational cohort study of evolving epidemiologic, clinical, and virologic features of monkeypox in Southern France

…, K Bendamardji, C Boschi, S Aherfi… - Emerging Infectious …, 2022 - ncbi.nlm.nih.gov
We enrolled 136 patients with laboratory-confirmed monkeypox during June 4–August 31,
2022, at the University Hospital Institute Méditerranée Infection in Marseille, France. The …

Drug repurposing against SARS-CoV-1, SARS-CoV-2 and MERS-CoV

S Aherfi, B Pradines, C Devaux, S Honore… - Future …, 2021 - Future Medicine
Since the beginning of the COVID-19 pandemic, large in silico screening studies and numerous
in vitro studies have assessed the antiviral activity of various drugs on SARS-CoV-2. In …

[HTML][HTML] Metabolic arsenal of giant viruses: Host hijack or self-use?

…, JJ Stegeman, P Colson, B La Scola, S Aherfi - Elife, 2022 - elifesciences.org
Viruses generally are defined as lacking the fundamental properties of living organisms in that
they do not harbor an energy metabolism system or protein synthesis machinery. However…

[HTML][HTML] Shan virus: a new mimivirus isolated from the stool of a Tunisian patient with pneumonia

H Saadi, DGI Reteno, P Colson, S Aherfi, P Minodier… - Intervirology, 2013 - karger.com
Objective: Following the isolation of a Marseillevirus from the stool of a healthy young Senegalese
and a Mimivirus from a Tunisian patient with pneumonia, we attempted to isolate other …

[HTML][HTML] Monitoring the circulation of SARS-CoV-2 variants by genomic analysis of wastewater in Marseille, South-East France

…, A Annessi, A Lacoste, P Colson, S Aherfi… - Pathogens, 2021 - mdpi.com
The monitoring of SARS-CoV-2 RNA in sewage has been proposed as a simple and
unbiased means of assessing epidemic evolution and the efficiency of the COVID-19 control …

[HTML][HTML] A large open pangenome and a small core genome for giant pandoraviruses

S Aherfi, J Andreani, E Baptiste… - Frontiers in …, 2018 - frontiersin.org
Giant viruses of amoebae are distinct from classical viruses by the giant size of their virions
and genomes. Pandoraviruses are the record holders in size of genomes and number of …