[HTML][HTML] Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-blind, randomised, placebo …

…, ER Ko, AP de Leon, SB Doernberg… - The lancet respiratory …, 2021 - thelancet.com
Background Functional impairment of interferon, a natural antiviral component of the
immune system, is associated with the pathogenesis and severity of COVID-19. We aimed to …

Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial

…, NM Iovine, HM El Sahly, SB Doernberg… - The lancet respiratory …, 2022 - thelancet.com
Background Baricitinib and dexamethasone have randomised trials supporting their use for
the treatment of patients with COVID-19. We assessed the combination of baricitinib plus …

Chronic meningitis investigated via metagenomic next-generation sequencing

…, BJ Brew, A Soldatos, L Strnad, SB Doernberg… - JAMA …, 2018 - jamanetwork.com
Importance Identifying infectious causes of subacute or chronic meningitis can be challenging.
Enhanced, unbiased diagnostic approaches are needed. Objective To present a case …

Ceftobiprole for Treatment of Complicated Staphylococcus aureus Bacteremia

TL Holland, SE Cosgrove, SB Doernberg… - … England Journal of …, 2023 - Mass Medical Soc
Background Ceftobiprole is a cephalosporin that may be effective for treating complicated
Staphylococcus aureus bacteremia, including methicillin-resistant S. aureus. Methods In this …

Randomized trial evaluating clinical impact of RAPid IDentification and susceptibility testing for gram-negative bacteremia: RAPIDS-GN

…, R Arias, W Swearingen, SB Doernberg… - Clinical Infectious …, 2021 - academic.oup.com
Background Rapid blood culture diagnostics are of unclear benefit for patients with gram-negative
bacilli (GNB) bloodstream infections (BSIs). We conducted a multicenter, randomized, …

Association of race/ethnicity with likeliness of COVID-19 vaccine uptake among health workers and the general population in the San Francisco Bay Area

…, M Desai, V Jain, C Lindan, SB Doernberg… - JAMA internal …, 2021 - jamanetwork.com
… Dr Doernberg reported receiving grants from the Chan Zuckerberg Initiative during the
conduct of the study and receiving personal fees from Genentech and Basilea Pharmaceutica for …

Essential resources and strategies for antibiotic stewardship programs in the acute care setting

SB Doernberg, LM Abbo, SD Burdette… - Clinical Infectious …, 2018 - academic.oup.com
Background Antibiotic stewardship programs improve clinical outcomes and patient safety
and help combat antibiotic resistance. Specific guidance on resources needed to structure …

[HTML][HTML] Clinical outcomes and serologic response in solid organ transplant recipients with COVID-19: a case series from the United States

M Fung, CY Chiu, C DeVoe, SB Doernberg… - American Journal of …, 2020 - Elsevier
The coronavirus disease 2019 (COVID-19) pandemic caused by SARS coronavirus 2 (SARS-CoV-2)
has caused significant morbidity and mortality for patients and stressed healthcare …

[HTML][HTML] Integrated host-microbe plasma metagenomics for sepsis diagnosis in a prospective cohort of critically ill adults

…, A Gomez, N Neff, A Pisco, SB Doernberg… - Nature …, 2022 - nature.com
We carried out integrated host and pathogen metagenomic RNA and DNA next generation
sequencing (mNGS) of whole blood (n = 221) and plasma (n = 138) from critically ill patients …

A retrospective, observational study of 12 cases of expanded-access customized phage therapy: production, characteristics, and clinical outcomes

…, S Aslam, JW Campbell, SB Doernberg… - Clinical Infectious …, 2023 - academic.oup.com
Background Antimicrobial resistance (AMR) is undermining modern medicine, a problem
compounded by bacterial adaptation to antibiotic pressures. Phages are viruses that infect …