User profiles for Sarah D. Linnstaedt
Sarah LinnstaedtAssistant Professor, University of North Carolina at Chapel Hill Verified email at med.unc.edu Cited by 2952 |
[HTML][HTML] International meta-analysis of PTSD genome-wide association studies identifies sex-and ancestry-specific genetic risk loci
…, LAM Lebois, CE Lewis, SD Linnstaedt… - Nature …, 2019 - nature.com
The risk of posttraumatic stress disorder (PTSD) following trauma is heritable, but robust
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD …
common variants have yet to be identified. In a multi-ethnic cohort including over 30,000 PTSD …
Virally induced cellular microRNA miR-155 plays a key role in B-cell immortalization by Epstein-Barr virus
SD Linnstaedt, E Gottwein, RL Skalsky… - Journal of …, 2010 - Am Soc Microbiol
Infection of resting primary human B cells by Epstein-Barr virus (EBV) results in their
transformation into indefinitely proliferating lymphoblastoid cell lines (LCLs). LCL formation serves …
transformation into indefinitely proliferating lymphoblastoid cell lines (LCLs). LCL formation serves …
[HTML][HTML] A viral microRNA cluster strongly potentiates the transforming properties of a human herpesvirus
R Feederle, SD Linnstaedt, H Bannert, H Lips… - PLoS …, 2011 - journals.plos.org
Epstein-Barr virus (EBV), an oncogenic human herpesvirus, induces cell proliferation after
infection of resting B lymphocytes, its reservoir in vivo. The viral latent proteins are necessary …
infection of resting B lymphocytes, its reservoir in vivo. The viral latent proteins are necessary …
The members of an Epstein-Barr virus microRNA cluster cooperate to transform B lymphocytes
R Feederle, J Haar, K Bernhardt, SD Linnstaedt… - Journal of …, 2011 - Am Soc Microbiol
Epstein-Barr virus (EBV) transforms B lymphocytes through the expression of the latent viral
proteins EBNA and latent membrane protein (LMP). Recently, it has become apparent that …
proteins EBNA and latent membrane protein (LMP). Recently, it has become apparent that …
Persistent dissociation and its neural correlates in predicting outcomes after trauma exposure
Objective: Dissociation, a disruption or discontinuity in psychological functioning, is often
linked with worse psychiatric symptoms; however, the prognostic value of dissociation after …
linked with worse psychiatric symptoms; however, the prognostic value of dissociation after …
Brain-based biotypes of psychiatric vulnerability in the acute aftermath of trauma
Objective: Major negative life events, such as trauma exposure, can play a key role in igniting
or exacerbating psychopathology. However, few disorders are diagnosed with respect to …
or exacerbating psychopathology. However, few disorders are diagnosed with respect to …
The Epstein-Barr virus (EBV)-induced tumor suppressor microRNA MiR-34a is growth promoting in EBV-infected B cells
…, SD Linnstaedt, E Gottwein, C Jacobs, D Jima… - Journal of …, 2012 - Am Soc Microbiol
Epstein-Barr virus (EBV) infection of primary human B cells drives their indefinite proliferation
into lymphoblastoid cell lines (LCLs). B cell immortalization depends on expression of viral …
into lymphoblastoid cell lines (LCLs). B cell immortalization depends on expression of viral …
Production of Muramic δ-Lactam in Bacillus subtilis Spore Peptidoglycan
…, AM Dean, SD Linnstaedt… - Journal of …, 2004 - Am Soc Microbiol
Bacterial spore heat resistance is primarily dependent upon dehydration of the spore
cytoplasm, a state that is maintained by the spore peptidoglycan wall, the spore cortex. A …
cytoplasm, a state that is maintained by the spore peptidoglycan wall, the spore cortex. A …
Development and validation of a model to predict posttraumatic stress disorder and major depression after a motor vehicle collision
Importance A substantial proportion of the 40 million people in the US who present to
emergency departments (EDs) each year after traumatic events develop posttraumatic stress …
emergency departments (EDs) each year after traumatic events develop posttraumatic stress …
[HTML][HTML] Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure
Considerable racial/ethnic disparities persist in exposure to life stressors and socioeconomic
resources that can directly affect threat neurocircuitry, particularly the amygdala, that …
resources that can directly affect threat neurocircuitry, particularly the amygdala, that …