User profiles for Sarah Filippi

Sarah Filippi

Senior Lecturer, Imperial College London
Verified email at imperial.ac.uk
Cited by 3064

Age groups that sustain resurging COVID-19 epidemics in the United States

…, VC Bradley, Y Chen, H Coupland, S Filippi… - Science, 2021 - science.org
INTRODUCTION After initial declines, in mid-2020, a sustained resurgence in the transmission
of novel coronavirus disease (COVID-19) occurred in the United States. Throughout the …

Parametric bandits: The generalized linear case

S Filippi, O Cappe, A Garivier… - Advances in neural …, 2010 - proceedings.neurips.cc
We consider structured multi-armed bandit tasks in which the agent is guided by prior
structural knowledge that can be exploited to efficiently select the optimal arm (s) in situations …

[HTML][HTML] Maximizing the information content of experiments in systems biology

J Liepe, S Filippi, M Komorowski… - PLoS computational …, 2013 - journals.plos.org
Our understanding of most biological systems is in its infancy. Learning their structure and
intricacies is fraught with challenges, and often side-stepped in favour of studying the function …

A framework for parameter estimation and model selection from experimental data in systems biology using approximate Bayesian computation

J Liepe, P Kirk, S Filippi, T Toni, CP Barnes… - Nature protocols, 2014 - nature.com
As modeling becomes a more widespread practice in the life sciences and biomedical
sciences, researchers need reliable tools to calibrate models against ever more complex and …

[HTML][HTML] State-level tracking of COVID-19 in the United States

…, MAC Vollmer, C Whittaker, SL Filippi… - Nature …, 2020 - nature.com
As of 1st June 2020, the US Centres for Disease Control and Prevention reported 104,232
confirmed or probable COVID-19-related deaths in the US. This was more than twice the …

Perturbation of fetal liver hematopoietic stem and progenitor cell development by trisomy 21

A Roy, G Cowan, AJ Mead, S Filippi… - Proceedings of the …, 2012 - National Acad Sciences
The 40-fold increase in childhood megakaryocyte-erythroid and B-cell leukemia in Down
syndrome implicates trisomy 21 (T21) in perturbing fetal hematopoiesis. Here, we show that …

On optimality of kernels for approximate Bayesian computation using sequential Monte Carlo

S Filippi, CP Barnes, J Cornebise… - Statistical applications in …, 2013 - degruyter.com
Approximate Bayesian computation (ABC) has gained popularity over the past few years for
the analysis of complex models arising in population genetics, epidemiology and system …

[HTML][HTML] Large-scale kernel methods for independence testing

Q Zhang, S Filippi, A Gretton, D Sejdinovic - Statistics and Computing, 2018 - Springer
Abstract Representations of probability measures in reproducing kernel Hilbert spaces provide
a flexible framework for fully nonparametric hypothesis tests of independence, which can …

Optimism in reinforcement learning and Kullback-Leibler divergence

S Filippi, O Cappé, A Garivier - 2010 48th Annual Allerton …, 2010 - ieeexplore.ieee.org
We consider model-based reinforcement learning in finite Markov Decision Processes (MDPs),
focussing on so-called optimistic strategies. In MDPs, optimism can be implemented by …

[HTML][HTML] Accelerated MRI-predicted brain ageing and its associations with cardiometabolic and brain disorders

A Kolbeinsson, S Filippi, Y Panagakis, PM Matthews… - Scientific Reports, 2020 - nature.com
Brain structure in later life reflects both influences of intrinsic aging and those of lifestyle,
environment and disease. We developed a deep neural network model trained on brain MRI …