MicroRNAs (miRNAs) are endogenously expressed noncoding RNAs that regulate mRNA
expression. In vertebrates, more distinct miRNAs are expressed in the brain than in any other …

Objective: Binge-eating disorder, the most prevalent eating disorder, is a serious public
health problem associated with obesity, psychiatric and medical comorbidities, and functional …

In mice, microRNAs (miRNAs) are required for embryonic viability, and previous reports
implicate miRNA participation in brain cortical neurogenesis. Here, we provide a more …

In the first poem of The Lichtenberg Figures, the contemporary poet Ben Lerner (son of
psychotherapist Harriet Lerner) captures the dynamics of a volatile romance. He opens with the …

Background Volatile interpersonal relationships are a core feature of borderline personality
disorder (BPD) and lead to devastating disruption of patients’ personal and professional lives…

MicroRNA (miRNA) function is required for normal animal development, in particular in
differentiation pathways from stem cell and precursor populations. In neurogenesis, it is …

We reconsider delusions in terms of a “doxastic shear pin”, a mechanism that errs so as to
prevent the destruction of the machine (brain) and permit continued function (in an attenuated …

This study is the first randomized controlled trial to test the effects of ketamine in Borderline
Personality Disorder (BPD). BPD remains undertreated in the community and no medication …

Background: Ketamine has emerged as one of the most promising therapies for treatment-resistant
depression. However, inter-individual variability in response to ketamine is still not …

Objective: Binge-eating disorder (BED), the most prevalent eating disorder, is a serious public
health problem associated with obesity, psychiatric/medical comorbidities, and functional …