A crowd of BashTheBug volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96 …

…, C Wright, H Spiers, T Zhu, EML Baeten, SW Hoosdally… - Elife, 2022 - elifesciences.org
Tuberculosis is a respiratory disease that is treatable with antibiotics. An increasing prevalence
of resistance means that to ensure a good treatment outcome it is desirable to test the …

BashTheBug: a crowd of volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96 …

…, C Wright, H Spiers, T Zhu, EML Baeten, SW Hoosdally… - bioRxiv, 2021 - biorxiv.org
Tuberculosis is a respiratory disease that is treatable with antibiotics. An increasing prevalence
of resistance means that to ensure a good treatment outcome it is desirable to test the …

[HTML][HTML] Antibody responses and correlates of protection in the general population after two doses of the ChAdOx1 or BNT162b2 vaccines

…, J Farrar, A Howarth, BD Marsden, S Hoosdally… - Nature Medicine, 2022 - nature.com
Antibody responses are an important part of immunity after Coronavirus Disease 2019 (COVID-19)
vaccination. However, antibody trajectories and the associated duration of protection …

The duration, dynamics, and determinants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody responses in individual healthcare workers

…, G Screaton, D Ebner, S Hoosdally… - Clinical Infectious …, 2021 - academic.oup.com
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin
G (IgG) antibody measurements can be used to estimate the proportion of a population …

The duration, dynamics and determinants of SARS-CoV-2 antibody responses in individual healthcare workers

…, DI Stuart, G Screaton, D Ebner, S Hoosdally… - MedRxiv, 2020 - medrxiv.org
Background SARS-CoV-2 IgG antibody measurements can be used to estimate the
proportion of a population exposed or infected and may be informative about the risk of future …

[HTML][HTML] Anti-spike antibody response to natural SARS-CoV-2 infection in the general population

…, A Howarth, BD Marsden, S Hoosdally… - Nature …, 2021 - nature.com
Understanding the trajectory, duration, and determinants of antibody responses after SARS-CoV-2
infection can inform subsequent protection and risk of reinfection, however large-…

[HTML][HTML] Protection against SARS-CoV-2 Omicron BA. 4/5 variant following booster vaccination or breakthrough infection in the UK

…, J Kolenchery, BD Marsden, S Hoosdally… - Nature …, 2023 - nature.com
Following primary SARS-CoV-2 vaccination, whether boosters or breakthrough infections
provide greater protection against SARS-CoV-2 infection is incompletely understood. Here we …

[HTML][HTML] The impact of sequencing depth on the inferred taxonomic composition and AMR gene content of metagenomic samples

…, MJ Bowes, MJ Bailey, TEA Peto, SJ Hoosdally… - Environmental …, 2019 - Springer
Background Shotgun metagenomics is increasingly used to characterise microbial communities,
particularly for the investigation of antimicrobial resistance (AMR) in different animal …

[HTML][HTML] SARS-CoV-2 antibody trajectories after a single COVID-19 vaccination with and without prior infection

…, J Farrar, A Howarth, BD Marsden, S Hoosdally… - Nature …, 2022 - nature.com
Given high SARS-CoV-2 incidence, coupled with slow and inequitable vaccine roll-out in
many settings, there is a need for evidence to underpin optimum vaccine deployment, aiming …

SARS-CoV-2 anti-spike IgG antibody responses after second dose of ChAdOx1 or BNT162b2 and correlates of protection in the UK general population

…, J Farrar, A Howarth, BD Marsden, S Hoosdally… - medRxiv, 2021 - medrxiv.org
We investigated anti-spike IgG antibody responses and correlates of protection following
second doses of ChAdOx1 or BNT162b2 SARS-CoV-2 vaccines in the UK general population. …