Objectives: To estimate the contribution of genes and shared family environment to the
liability toDSM-IVmajor depression and to examine the influence of certain proband …

Cardiac hypertrophy is a major risk factor for heart failure and associated patient morbidity
and mortality. Research investigating the aberrant molecular processes that occur during …

Deficits in phonological skills appear to be at the heart of reading disability; however, the nature
of this impairment is not yet known. The hypothesis that dyslexic subjects are impaired in …

Cover. True-color moderate resolution imaging spectroradiometer (MODIS) satellite image
05292003 showing the eight principal islands of the Hawaiian Island chain from May 21, 2003…

Background Psoriasis is a common inflammatory skin disease that has been reported to be
associated with obesity. We aimed to investigate a possible causal relationship between …

Epigenome-wide association studies (EWAS) seek to quantify associations between traits/exposures
and DNA methylation measured at thousands or millions of CpG sites across the …

Background Engagement in multiple risk behaviours can have adverse consequences for
health during childhood, during adolescence, and later in life, yet little is known about the …

Background—Gene transfer to vascular cells is a highly inefficient and nonselective process,
defined by the lack of specific cell-surface receptors for both nonviral and viral gene …

Cardiac hypertrophy occurs as an adaptation to hypertension but a sustained hypertrophic
response can ultimately lead to heart failure. Angiotensin-II (Ang II) is released following …

Background High profile accounts of failures in patient care reflect an urgent need for
transformational development in healthcare. Appreciative Inquiry is promoted as an approach to …