Synthetic biology holds promise as both a framework for rationally engineering biological
systems and a way to revolutionize how we fundamentally understand them. Essential to …

Regulatory RNAs have become integral components of the synthetic biology and bioengineering
toolbox for controlling gene expression. We recently expanded this toolbox by creating …

The lactose repressor (LacI) is a classic genetic switch that has been used as a fundamental
component in a host of synthetic genetic networks. To expand the function of LacI for use in …

To expand our understanding of the hallmarks of allosteric control we used directed-evolution
to engineer alternate cooperative communication in the lactose repressor protein (LacI) …

A large number of bacteria have been found to govern virulence and heat shock responses
using temperature-sensing RNAs known as RNA thermometers. A prime example is the …

The ability to predictably and accurately control gene expression is a fundamental requirement
for synthetic biologists as they seek to harness the power of cellular machinery for real-…

Graphene has been under intense investigation since the seminal work of Novoselov and
Geim in which they isolated few-layer and single-layer graphene [2]. This was accomplished …

Background Rotors have been postulated to be a major driver of atrial fibrillation (AF). Initial
studies demonstrated, that focal impulse and rotor modulation (FIRM) might be an effective …

… In 2011 he married his high school sweetheart, Sarai Meyer (Itagaki), and they moved to
Ithaca, New York to begin their Ph.Ds at Cornell University. Michael entered the TriInstitutional …

Individual ion channels or exchangers are described with a common set of equetions for both
the sinoatrial node pacemaker and ventricular cells. New experimental data are included, …