User profiles for Saranya Canchi

Saranya Canchi

UC Davis
Verified email at ucdavis.edu
Cited by 296

[PDF][PDF] Integrating gene and protein expression reveals perturbed functional networks in Alzheimer's disease

S Canchi, B Raao, D Masliah, SB Rosenthal, R Sasik… - Cell reports, 2019 - cell.com
Asymptomatic and symptomatic Alzheimer's disease (AD) subjects may present with equivalent
neuropathological burdens but have significantly different antemortem cognitive decline …

[HTML][HTML] Transcriptomic analysis of brain tissues identifies a role for CCAAT enhancer binding protein β in HIV-associated neurocognitive disorder

S Canchi, MK Swinton, RA Rissman… - Journal of …, 2020 - Springer
Background HIV-associated neurocognitive disorders (HAND) persist in the era of combined
antiretroviral therapy (ART) despite reductions in viral load (VL) and overall disease severity…

[HTML][HTML] A transcriptome-wide association study of Alzheimer's disease using prediction models of relevant tissues identifies novel candidate susceptibility genes

Y Sun, J Zhu, D Zhou, S Canchi, C Wu, NJ Cox… - Genome medicine, 2021 - Springer
Background Genome-wide association studies (GWAS) have identified over 56 susceptibility
loci associated with Alzheimer’s disease (AD), but the genes responsible for these …

Controlled single bubble cavitation collapse results in jet-induced injury in brain tissue

S Canchi, K Kelly, Y Hong, MA King, G Subhash… - Journal of the …, 2017 - Elsevier
Multiscale damage due to cavitation is considered as a potential mechanism of traumatic
brain injury (TBI) associated with explosion. In this study, we employed a TBI relevant …

Making Common Fund data more findable: catalyzing a data ecosystem

…, A Brady, K Czajkowski, J Aluvathingal, S Canchi… - …, 2022 - academic.oup.com
The Common Fund Data Ecosystem (CFDE) has created a flexible system of data federation
that enables researchers to discover datasets from across the US National Institutes of …

[HTML][HTML] Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2

J Ngolab, S Canchi, S Rasool, A Elmaarouf… - Neurobiology of …, 2021 - Elsevier
The microtubule-associated protein tau is implicated in multiple degenerative diseases including
retinal diseases such as glaucoma; however, the way tau initiates retinopathy is unclear…

[HTML][HTML] Simulated blast overpressure induces specific astrocyte injury in an ex vivo brain slice model

S Canchi, M Sarntinoranont, Y Hong, JJ Flint… - PloS one, 2017 - journals.plos.org
Exposure to explosive blasts can produce functional debilitation in the absence of brain
pathology detectable at the scale of current diagnostic imaging. Transient (ms) overpressure …

[HTML][HTML] Role of re-entry tears on the dynamics of type B dissection flap

S Canchi, X Guo, M Phillips, Z Berwick… - Annals of Biomedical …, 2018 - Springer
Mortality during follow-up after acute Type B aortic dissection is substantial with aortic expansion
observed in over 59% of the patients. Lumen pressure differential is considered a prime …

Damage in brain tissue due to single bubble cavitation shock

G Subhash, S Canchi, Y Hong… - Mechanics of Biological …, 2016 - Springer
A novel experimental technique was developed to visualize and control single bubble
cavitation initiation, growth, and its collapse. The influence of this process on a nearby tissue …

[PDF][PDF] Virtual training on virtual environments: an online open-source introduction to conda

MCW Lim, A Parigi, S Canchi, J Sanchez… - Journal of Open …, 2021 - jose.theoj.org
We present our lesson material and resources for teaching how to use conda (https://conda.
io), a tool that streamlines software installation and version management using isolated …