Deep reinforcement learning for optimal critical care pain management with morphine using dueling double-deep Q networks

…, P Eschenfeldt, S Ostvar… - 2019 41st Annual …, 2019 - ieeexplore.ieee.org
Opioids are the preferred medications for the treatment of pain in the intensive care unit.
While under-treatment leads to unrelieved pain and poor clinical outcomes, excessive use of …

Multiscale model describing bacterial adhesion and detachment

S Ostvar, BD Wood - Langmuir, 2016 - ACS Publications
Bacterial surfaces are complex structures with nontrivial adhesive properties. The physics of
bacterial adhesion deviates from that of ideal colloids as a result of cell-surface roughness …

Association of neighborhood deprivation index with success in cancer care crowdfunding

ER Silver, HQ Truong, S Ostvar, C Hur… - JAMA Network …, 2020 - jamanetwork.com
Importance Financial toxicity resulting from cancer care poses a substantial public health
concern, leading some patients to turn to online crowdfunding. However, the practice may …

Investigating the influence of flow rate on biofilm growth in three dimensions using microimaging

S Ostvar, G Iltis, Y Davit, S Schlüter, L Andersson… - Advances in water …, 2018 - Elsevier
We explore how X-ray computed microtomography can be used to generate highly-resolved
3D biofilm datasets on length scales that span multiple pore bodies. The data is integrated …

[HTML][HTML] Mechanical control of neural plate folding by apical domain alteration

M Matsuda, J Rozman, S Ostvar, KE Kasza… - Nature …, 2023 - nature.com
Vertebrate neural tube closure is associated with complex changes in cell shape and
behavior, however, the relative contribution of these processes to tissue folding is not well …

Cost‐effectiveness of immune checkpoint inhibitors for microsatellite instability–high/mismatch repair–deficient metastatic colorectal cancer

JN Chu, J Choi, S Ostvar, JA Torchia, KL Reynolds… - Cancer, 2019 - Wiley Online Library
Background Patients with microsatellite instability–high (MSI‐H)/mismatch repair–deficient (dMMR)
metastatic colorectal cancer (mCRC) show a significant response to checkpoint …

A non-scale-invariant form for coarse-grained diffusion-reaction equations

S Ostvar, BD Wood - The Journal of Chemical Physics, 2016 - pubs.aip.org
The process of mixing and reaction is a challenging problem to understand mathematically.
Although there have been successes in describing the effective properties of mixing and …

Modeling transport of chemotactic bacteria in granular media with distributed contaminant sources

JST Adadevoh, S Ostvar, B Wood… - Environmental science & …, 2017 - ACS Publications
Chemotaxis has the potential to improve bioremediation strategies by enhancing the
transport of pollutant-degrading bacteria to the source of contamination, leading to increased …

Atomic force microscopy and wettability study of the alteration of mica and sandstone by a biosurfactant-producing bacterium Bacillus thermodenitrificans

S Zargari, S Ostvar, A Niazi… - Journal of Advanced …, 2010 - ingentaconnect.com
The effects of growth and metabolite production of a variant of Bacillus thermodenitrificans
on the surface properties and wettability of mica and sandstone cores were investigated. …

Optimizing management of patients with Barrett's esophagus and low-grade or no dysplasia based on comparative modeling

…, M Lee, SK Naber, BN Lauren, S Ostvar… - Clinical …, 2020 - Elsevier
Background & Aims Endoscopic treatment is recommended for patients with Barrett’s
esophagus (BE) with high-grade dysplasia, yet clinical management recommendations are …