Manipulation of the gut microbiota holds great promise for the treatment of inflammatory and
allergic diseases 1 , 2 . Although numerous probiotic microorganisms have been identified 3 …

Tumor growth is associated with aberrant myelopoiesis, including the accumulation of CD11b
+ Gr-1 + myeloid-derived suppressor cells (MDSCs) that have the potential to promote …

Langerhans cells (LCs) are epidermal dendritic cells with incompletely understood origins
that associate with hair follicles for unknown reasons. Here we show that in response to …

The mechanisms underlying immune tolerance during pregnancy are poorly understood. In
this regard, Treg seem to play an important role in mediating maternal tolerance to the fetus. …

Fibrocytes are a distinct population of bloodborne cells that share markers of leukocytes as
well as mesenchymal cells. We hypothesized that CCR7-positive fibrocytes migrate into the …

Recruitment of dendritic cells (DCs) to lymph nodes (LNs) is pivotal to the establishment of
immune response. Whereas DCs have been proven to undergo afferent lymphatic pathway to …

Resident memory T cells (T RM cells) are an important first-line defense against respiratory
pathogens, but the unique contributions of lung T RM cell populations to protective immunity …

Organ fibrosis is a pathological condition associated with chronic inflammatory diseases. In
fibrosis, excessive deposition of extracellular matrix (ECM) severely impairs tissue …

Skin-derived dendritic cells (DCs) play a crucial role in the maintenance of immune homeostasis
due to their role in antigen trafficking from the skin to the draining lymph nodes (dLNs). …

Cell senescence plays a key role in age-associated organ dysfunction, but the in vivo
pathogenesis is largely unclear. Here, we generated a p16-Cre ERT2 -tdTomato mouse model to …