User profiles for Savini Thrikawala

Savini Thrikawala

Clemson University
Verified email at clemson.edu
Cited by 73

Triazole fungicides induce adipogenesis and repress osteoblastogenesis in zebrafish

S Thrikawala, F Mesmar, B Bhattacharya… - Toxicological …, 2023 - academic.oup.com
Triazoles are a major group of azole fungicides commonly used in agriculture, and veterinary
and human medicine. Maternal exposure to certain triazole antifungal medication causes …

Differential activity of BPA, BPAF and BPC on zebrafish estrogen receptors in vitro and in vivo

C Pinto, R Hao, M Grimaldi, S Thrikawala… - Toxicology and applied …, 2019 - Elsevier
The high volume production compound bisphenol A (BPA) is of environmental concern largely
because of its estrogenic activity. Consequently, BPA analogues have been synthesized …

[HTML][HTML] Cyclooxygenase production of PGE2 promotes phagocyte control of A. fumigatus hyphal growth in larval zebrafish

S Thrikawala, M Niu, NP Keller, EE Rosowski - PLoS Pathogens, 2022 - journals.plos.org
Invasive aspergillosis is a common opportunistic infection, causing >50% mortality in infected
immunocompromised patients. The specific molecular mechanisms of the innate immune …

Glucocorticoids suppress NF-κB-mediated neutrophil control of Aspergillus fumigatus hyphal growth

SU Thrikawala, M Anderson, EE Rosowski - bioRxiv, 2023 - biorxiv.org
Glucocorticoids are a major class of therapeutic anti-inflammatory and immunosuppressive
drugs prescribed to patients with inflammatory diseases, to avoid transplant rejection, and as …

Infection of zebrafish larvae with aspergillus spores for analysis of host-pathogen interactions

S Thrikawala, EE Rosowski - JoVE (Journal of Visualized Experiments), 2020 - jove.com
Invasive aspergillosis (IA) is one of the most common fungal infections among immunocompromised
individuals. Despite the availability of antifungal drugs, IA can cause >50% mortality …

Developing the Zebrafish Neuromast Assay as a Predictive Toxicity Model

R Mirchandani, S Thrikawala, C Stephan, N Nguyen… - 2017 - uh-ir.tdl.org
We developed a method for rapid screening of large number of chemicals to identify zebrafish
neuromast disruptors. We identified serotonin as a possible pathway being targeted by the …

Developmental Malformations in Zebrafish Caused by Exposure to Environmental Pollutants

SU Thrikawala - 2018 - search.proquest.com
It is estimated that there are about 80,000 man-made chemicals released to the environment
with little to no toxicity information. Exposure to these chemicals is identified as one of the …

Environmental Pollutants Disrupting Nuclear Receptor Signaling and Metabolism in Zebrafish

S Kalasekar - 2015 - uh-ir.tdl.org
… , Savini Thrikawala and Rachna Sach for their hard work, coordinated team efforts, and
adding new zing to the lab, Stephanie Sandri, and Drs. Ruixin Hao and Nicole Ducharme. …

Effects of Pyriproxyfen Exposure on Nervous System Develpment in Zebrafish

S Thrikawala, JÅ Gustafsson, M Bondesson - 2017 - uh-ir.tdl.org
Pyriproxyfen is used in agricultural and veterinary pests. It is also used to treat drinking water
sources, to prevent mosquito breeding. Therefore, it is debated that pyriproxyfen treated …

Pipeline for the Zebrafish Model as a Predictor of Specific Teratogenic Effects

R Mirchandani - 2020 - search.proquest.com
Savini Thrikawala, my closest friend, a wonderful colleague, and one of the most encouraging
influences in my life. She would continue believing in me even when I wouldn’t, and she …