Repurposing FDA-approved drugs is an efficient and cost-effective approach in the development
of therapeutics for a broad range of diseases. However, prediction of function can be …

Brain function studies greatly depend on quantification and analysis of behavior. While
behavior can be imaged efficiently, the quantification of specific aspects of behavior is labor-…

Matrix metalloproteinase-9 (MMP-9) is a secreted endopeptidase targeting extracellular
matrix proteins, creating permissive environments for neuronal development and plasticity. …

Drug repurposing can accelerate drug development while reducing the cost and risk of toxicity
typically associated with de novo drug design. Several disorders lacking pharmacological …

Introduction Animals respond to various environmental cues. Animal behavior is complex,
and behavior analysis can greatly help to understand brain function. Most of the available …

The analysis of mouse behavior is used in biomedical research to study brain function in
health and disease. Well-established rapid assays allow for high-throughput analyses of …

Results of recent work from our labs and those of others have broadened perspectives on
addiction beyond a human-specific, cognitive phenomenon. Addictive plant alkaloids are …

Synthetic cathinones share potent sympathomimetic properties with amphetamines due to
their shared phenethylamine backbone. Despite recent work focused on understanding the …

Drug repurposing can accelerate drug development while reducing the cost and risk of toxicity
typically associated with de novo drug design. Several disorders lacking pharmacological …

Matrix metalloproteinase-9 (MMP-9) is a secreted endopeptidase targeting extracellular
matrix proteins, creating permissive environments for neuronal development and plasticity. …