Children and youth infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
have milder disease than do adults, and even among those with the recently …

Viral infections continue to represent major challenges to public health, and an enhanced
mechanistic understanding of the processes that contribute to viral life cycles is necessary for …

TYRO3, AXL, and MER receptors (TAMs) are three homologous type I receptor-tyrosine
kinases that are activated by endogenous ligands, protein S (PROS1) and growth arrest-specific …

Large-scale activity profiling of enzyme superfamilies provides information about cellular
functions as well as the intrinsic binding capabilities of conserved folds. Herein, the functional …

Coronavirus disease 2019 (COVID-19) is a global health crisis caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and there is a critical need to …

Phosphate import is required for the growth of mycobacteria and is regulated by environmental
inorganic phosphate (P i ) concentrations, although the mechanism of this regulation has …

MERTK, a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinases, has
complex and diverse roles in cell biology. On the one hand, knock-out of MERTK results in age-…

Convalescent plasma with severe acute respiratory disease coronavirus 2 (SARS-CoV-2)
antibodies (CCP) may hold promise as a treatment for coronavirus disease 2019 (COVID-19). …

Aerobic organisms have a tricarboxylic acid (TCA) cycle that is functionally distinct from
those found in anaerobic organisms. Previous reports indicate that the aerobic pathogen …

The immune system’s ability to recognize peptides on major histocompatibility molecules
contributes to the eradication of cancers and pathogens. Tracking these responses in vivo …