User profiles for Scott J. Garforth
Scott J. GarforthAlbert Einstein College of Medicine Verified email at einsteinmed.org Cited by 2310 |
Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients
Children and youth infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
have milder disease than do adults, and even among those with the recently …
have milder disease than do adults, and even among those with the recently …
A naturally occurring antiviral ribonucleotide encoded by the human genome
Viral infections continue to represent major challenges to public health, and an enhanced
mechanistic understanding of the processes that contribute to viral life cycles is necessary for …
mechanistic understanding of the processes that contribute to viral life cycles is necessary for …
[HTML][HTML] Receptor tyrosine kinases, TYRO3, AXL, and MER, demonstrate distinct patterns and complex regulation of ligand-induced activation
…, KQN Nguyen, DA Calarese, SJ Garforth… - Journal of Biological …, 2014 - ASBMB
TYRO3, AXL, and MER receptors (TAMs) are three homologous type I receptor-tyrosine
kinases that are activated by endogenous ligands, protein S (PROS1) and growth arrest-specific …
kinases that are activated by endogenous ligands, protein S (PROS1) and growth arrest-specific …
Panoramic view of a superfamily of phosphatases through substrate profiling
…, RD Seidel, BS Hillerich, SJ Garforth… - Proceedings of the …, 2015 - National Acad Sciences
Large-scale activity profiling of enzyme superfamilies provides information about cellular
functions as well as the intrinsic binding capabilities of conserved folds. Herein, the functional …
functions as well as the intrinsic binding capabilities of conserved folds. Herein, the functional …
Characterization of the SARS-CoV-2 S protein: biophysical, biochemical, structural, and antigenic analysis
Coronavirus disease 2019 (COVID-19) is a global health crisis caused by the novel severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and there is a critical need to …
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and there is a critical need to …
The Two-Component Regulatory System senX3-regX3 Regulates Phosphate-Dependent Gene Expression in Mycobacterium smegmatis
RT Glover, J Kriakov, SJ Garforth… - Journal of …, 2007 - Am Soc Microbiol
Phosphate import is required for the growth of mycobacteria and is regulated by environmental
inorganic phosphate (P i ) concentrations, although the mechanism of this regulation has …
inorganic phosphate (P i ) concentrations, although the mechanism of this regulation has …
[HTML][HTML] Overexpression of MERTK receptor tyrosine kinase in epithelial cancer cells drives efferocytosis in a gain-of-function capacity
…, S Hsieh, Y Liu, B Lu, Y Wu, SJ Garforth… - Journal of Biological …, 2014 - ASBMB
MERTK, a member of the TAM (TYRO3, AXL, and MERTK) receptor tyrosine kinases, has
complex and diverse roles in cell biology. On the one hand, knock-out of MERTK results in age-…
complex and diverse roles in cell biology. On the one hand, knock-out of MERTK results in age-…
[HTML][HTML] Treatment of severe COVID-19 with convalescent plasma in Bronx, NYC
Convalescent plasma with severe acute respiratory disease coronavirus 2 (SARS-CoV-2)
antibodies (CCP) may hold promise as a treatment for coronavirus disease 2019 (COVID-19). …
antibodies (CCP) may hold promise as a treatment for coronavirus disease 2019 (COVID-19). …
[HTML][HTML] An Anaerobic-Type α-Ketoglutarate Ferredoxin Oxidoreductase Completes the Oxidative Tricarboxylic Acid Cycle of Mycobacterium tuberculosis
Aerobic organisms have a tricarboxylic acid (TCA) cycle that is functionally distinct from
those found in anaerobic organisms. Previous reports indicate that the aerobic pathogen …
those found in anaerobic organisms. Previous reports indicate that the aerobic pathogen …
In vivo detection of antigen-specific CD8+ T cells by immuno-positron emission tomography
…, M Rashidian, RJ Chaparro, RD Seidel, SJ Garforth… - Nature …, 2020 - nature.com
The immune system’s ability to recognize peptides on major histocompatibility molecules
contributes to the eradication of cancers and pathogens. Tracking these responses in vivo …
contributes to the eradication of cancers and pathogens. Tracking these responses in vivo …