User profiles for Scott Stagg

Scott Stagg

Florida State University
Verified email at fsu.edu
Cited by 6918

Automated molecular microscopy: the new Leginon system

…, A Cheng, F Guerra, J Quispe, S Stagg… - Journal of structural …, 2005 - Elsevier
We report here on the current state of our efforts in automated molecular microscopy. Our
primary automated data acquisition software system, Leginon, has been completely …

Structure of the Sec13/31 COPII coat cage

SM Stagg, C Gürkan, DM Fowler, P LaPointe, TR Foss… - Nature, 2006 - nature.com
Endomembranes of eukaryotic cells are dynamic structures that are in continuous communication
through the activity of specialized cellular machineries 1 , such as the coat protein …

[HTML][HTML] Study of the structural dynamics of the E. coli 70S ribosome using real-space refinement

…, M Valle, A Korostelev, N Eswar, SM Stagg… - Cell, 2003 - cell.com
Cryo-EM density maps showing the 70S ribosome of E. coli in two different functional states
related by a ratchet-like motion were analyzed using real-space refinement. Comparison of …

[HTML][HTML] Structural basis for cargo regulation of COPII coat assembly

SM Stagg, P LaPointe, A Razvi, C Gürkan, CS Potter… - Cell, 2008 - cell.com
Using cryo-electron microscopy, we have solved the structure of an icosidodecahedral
COPII coat involved in cargo export from the endoplasmic reticulum (ER) coassembled from …

Incorporation of aminoacyl-tRNA into the ribosome as seen by cryo-electron microscopy

M Valle, A Zavialov, W Li, SM Stagg, J Sengupta… - Nature structural …, 2003 - nature.com
Aminoacyl-tRNAs (aa-tRNAs) are delivered to the ribosome as part of the ternary complex
of aa-tRNA, elongation factor Tu (EF-Tu) and GTP. Here, we present a cryo-electron …

The COPII cage: unifying principles of vesicle coat assembly

C Gürkan, SM Stagg, P LaPointe… - Nature Reviews Molecular …, 2006 - nature.com
Communication between compartments of the exocytic and endocytic pathways in eukaryotic
cells involves transport carriers — vesicles and tubules — that mediate the vectorial …

Appion: an integrated, database-driven pipeline to facilitate EM image processing

GC Lander, SM Stagg, NR Voss, A Cheng… - Journal of structural …, 2009 - Elsevier
The use of cryoEM and three-dimensional image reconstruction is becoming increasingly
common. Our vision for this technique is to provide a straightforward manner in which users …

[HTML][HTML] ATP-triggered conformational changes delineate substrate-binding and-folding mechanics of the GroEL chaperonin

DK Clare, D Vasishtan, S Stagg, J Quispe, GW Farr… - Cell, 2012 - cell.com
The chaperonin GroEL assists the folding of nascent or stress-denatured polypeptides by
actions of binding and encapsulation. ATP binding initiates a series of conformational changes …

The Rules

…, M Sanner, T Shaikh, S Stagg… - Center for Integrative …, 2005 - nramm.nysbc.org
… Rossmann Michel Sanner Tanvir Shaikh Scott Stagg Vinzenz Unger Nigel Unwin Niels
Volkmann Thomas Walz Andrew Ward Liz Wilson-Kubalek Xiaodong Yan Mark Yeager …

[PDF][PDF] Structure of an RNA silencing complex of the CRISPR-Cas immune system

…, Y Shao, N Ramia, R Terns, M Terns, H Li, S Stagg - Molecular cell, 2013 - cell.com
Bacterial and archaeal clustered regularly interspaced short palindromic repeat (CRISPR)
loci capture virus and plasmid sequences and use them to recognize and eliminate these …