To the Editor—Rapid advances in DNA-sequencing and bioinformatics technologies in the
past two decades have substantially improved understanding of the microbial world. This …

Variation in the human gut microbiome can reflect host lifestyle and behaviors and influence
disease biomarker levels in the blood. Understanding the relationships between gut …

Industrialization has impacted the human gut ecosystem, resulting in altered microbiome
composition and diversity. Whether bacterial genomes may also adapt to the industrialization of …

Our growing awareness of the microbial world’s importance and diversity contrasts starkly
with our limited understanding of its fundamental structure. Despite recent advances in DNA …

The bacteria that colonize humans and our built environments have the potential to influence
our health. Microbial communities associated with seven families and their homes over 6 …

Hundreds of clinical studies have demonstrated associations between the human microbiome
and disease, yet fundamental questions remain on how we can generalize this knowledge…

Circadian clocks and metabolism are inextricably intertwined, where central and hepatic
circadian clocks coordinate metabolic events in response to light-dark and sleep-wake cycles. …

We present a performance-optimized algorithm, subsampled open-reference OTU picking,
for assigning marker gene (eg, 16S rRNA) sequences generated on next-generation …

The gut microbiome has important effects on human health, yet its importance in human
ageing remains unclear. In the present study, we demonstrate that, starting in mid-to-late …

Our understanding of how the gut microbiome interacts with its human host has been
restrained by limited access to longitudinal datasets to examine stability and dynamics, and by …