[HTML][HTML] High resolution mapping of the tumor microenvironment using integrated single-cell, spatial and in situ analysis
…, J Abousoud, TY Drennon, SH Mohabbat… - Nature …, 2023 - nature.com
Single-cell and spatial technologies that profile gene expression across a whole tissue are
revolutionizing the resolution of molecular states in clinical samples. Current commercially …
revolutionizing the resolution of molecular states in clinical samples. Current commercially …
Neuronal-epithelial cross-talk drives acinar specification via NRG1-ERBB3-mTORC2 signaling
…, N Cruz-Pacheco, E Emmerson, S Mohabbat… - Developmental cell, 2022 - cell.com
Acinar cells are the principal secretory units of multiple exocrine organs. A single-cell, layered,
lumenized acinus forms from a large cohort of epithelial progenitors that must initiate and …
lumenized acinus forms from a large cohort of epithelial progenitors that must initiate and …
Long-term functional regeneration of radiation-damaged salivary glands through delivery of a neurogenic hydrogel
J Li, S Sudiwala, L Berthoin, S Mohabbat… - Science …, 2022 - science.org
Salivary gland acinar cells are severely depleted after radiotherapy for head and neck cancer,
leading to loss of saliva and extensive oro-digestive complications. With no regenerative …
leading to loss of saliva and extensive oro-digestive complications. With no regenerative …
92 Characterization of the tumor microenvironment using the xenium in situ platform and FFPE tissue array technology
A Kalaimani, A Kim, J Berridge, B Nguyen, S Mohabbat… - 2023 - jitc.bmj.com
Background Tissue array technology enables screening of multiple tissue samples on a
single microscopic slide and is an assistive tool in the field of oncology, given its ability to …
single microscopic slide and is an assistive tool in the field of oncology, given its ability to …
Programmatic Building of a Secretory Acinus is Driven by Neuronal-Epithelial NRG1-ERBB3-mTORC2 Signaling
…, E Emmerson, S Sudiwala, S Mohabbat… - Available at SSRN … - papers.ssrn.com
Acinar cells are the principal secretory unit of multiple exocrine organs. A single cell layered,
lumenized acinus forms from a large cohort of epithelial progenitors that must initiate and …
lumenized acinus forms from a large cohort of epithelial progenitors that must initiate and …
High resolution mapping of the breast cancer tumor microenvironment using integrated single cell, spatial and in situ analysis of FFPE tissue
…, J Abousoud, C Morrison, TY Drennon, S Mohabbat… - BioRxiv, 2022 - biorxiv.org
Single cell and spatial technologies that profile gene expression across a whole tissue are
revolutionizing the resolution of molecular states in clinical tissue samples. Commercially …
revolutionizing the resolution of molecular states in clinical tissue samples. Commercially …
Generalization of deep learning models for predicting spatial gene expression profiles using histology images: A breast cancer case study
Spatial transcriptomics is a breakthrough technology that enables spatially-resolved
measurement of molecular profiles in tissues, opening the opportunity for integrated analyses of …
measurement of molecular profiles in tissues, opening the opportunity for integrated analyses of …
[HTML][HTML] Computational Frameworks for Functional Subcellular Analysis of Spatial Transcriptomics Data
CK Mah - 2023 - search.proquest.com
Emerging genomic technologies that measure spatial information about RNA molecules
promise to shed light on cell biology and function. However, most analytical techniques have …
promise to shed light on cell biology and function. However, most analytical techniques have …
[CITATION][C] 10x Development Teams, and Sarah EB Taylor
…, J Abousoud, CA Morrison, TY Drennon, SH Mohabbat… - … and in situ analysis of FFPE …, 2022
[CITATION][C] Visium CytAssist: A Novel Platform for Spatial Transcriptomic Analysis of FFPE Sections Mounted on Standard Glass Slides
…, D Sukovich, S Mohabbat… - MOLECULAR …, 2022 - CELL PRESS 50 HAMPSHIRE ST …