User profiles for Sebastian H Bitzenhofer
Sebastian H. BitzenhoferUniversity Medical Center Hamburg-Eppendorf Verified email at zmnh.uni-hamburg.de Cited by 639 |
[HTML][HTML] Layer-specific optogenetic activation of pyramidal neurons causes beta–gamma entrainment of neonatal networks
Coordinated activity patterns in the developing brain may contribute to the wiring of neuronal
circuits underlying future behavioural requirements. However, causal evidence for this …
circuits underlying future behavioural requirements. However, causal evidence for this …
Rapid odor processing by layer 2 subcircuits in lateral entorhinal cortex
Olfactory information is encoded in lateral entorhinal cortex (LEC) by two classes of layer 2 (L2)
principal neurons: fan and pyramidal cells. However, the functional properties of L2 cells …
principal neurons: fan and pyramidal cells. However, the functional properties of L2 cells …
Gamma activity accelerates during prefrontal development
Gamma oscillations are a prominent activity pattern in the cerebral cortex. While gamma
rhythms have been extensively studied in the adult prefrontal cortex in the context of cognitive (…
rhythms have been extensively studied in the adult prefrontal cortex in the context of cognitive (…
[PDF][PDF] A transient developmental increase in prefrontal activity alters network maturation and causes cognitive dysfunction in adult mice
Disturbed neuronal activity in neuropsychiatric pathologies emerges during development and
might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic growth, …
might cause multifold neuronal dysfunction by interfering with apoptosis, dendritic growth, …
Blood pressure pulsations modulate central neuronal activity via mechanosensitive ion channels
L Jammal Salameh, SH Bitzenhofer, IL Hanganu-Opatz… - Science, 2024 - science.org
The transmission of the heartbeat through the cerebral vascular system causes intracranial
pressure pulsations. We discovered that arterial pressure pulsations can directly modulate …
pressure pulsations. We discovered that arterial pressure pulsations can directly modulate …
[PDF][PDF] Resolving and rescuing developmental miswiring in a mouse model of cognitive impairment
…, V Oberländer, X Xu, J Ahlbeck, SH Bitzenhofer… - Neuron, 2020 - cell.com
Cognitive deficits, core features of mental illness, largely result from dysfunction of prefrontal
networks. This dysfunction emerges during early development, before a detectable …
networks. This dysfunction emerges during early development, before a detectable …
[HTML][HTML] Spindle activity orchestrates plasticity during development and sleep
C Lindemann, J Ahlbeck, SH Bitzenhofer… - Neural …, 2016 - hindawi.com
Spindle oscillations have been described during early brain development and in the adult
brain. Besides similarities in temporal patterns and involved brain areas, neonatal spindle …
brain. Besides similarities in temporal patterns and involved brain areas, neonatal spindle …
[PDF][PDF] Oscillatory activity in developing prefrontal networks results from theta-gamma-modulated synaptic inputs
SH Bitzenhofer, K Sieben, KD Siebert, M Spehr… - Cell reports, 2015 - cell.com
The hippocampus-driven entrainment of neonatal prefrontal circuits in theta-gamma
oscillations contributes to the maturation of cognitive abilities, yet the underlying synaptic …
oscillations contributes to the maturation of cognitive abilities, yet the underlying synaptic …
[HTML][HTML] Tapered fibers combined with a multi-electrode array for optogenetics in mouse medial prefrontal cortex
L Sileo, SH Bitzenhofer, B Spagnolo… - Frontiers in …, 2018 - frontiersin.org
Optogenetics offers many advantages in terms of cell-type specificity, allowing to investigate
functional connectivity between different brain areas at high spatial and neural population …
functional connectivity between different brain areas at high spatial and neural population …
[PDF][PDF] Olfactory bulb activity shapes the development of entorhinal-hippocampal coupling and associated cognitive abilities
YN Chen, JK Kostka, SH Bitzenhofer… - Current Biology, 2023 - cell.com
The interplay between olfaction and higher cognitive processing has been documented in
the adult brain; however, its development is poorly understood. In mice, shortly after birth, …
the adult brain; however, its development is poorly understood. In mice, shortly after birth, …