User profiles for Sebastian J. Arnold
Sebastian ArnoldUniversity of Freiburg, Institute of Pharmacology Verified email at pharmakol.uni-freiburg.de Cited by 7701 |
[PDF][PDF] Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages
Innate lymphoid cells (ILCs) are a recently recognized group of lymphocytes that have
important functions in protecting epithelial barriers against infections and in maintaining organ …
important functions in protecting epithelial barriers against infections and in maintaining organ …
Making a commitment: cell lineage allocation and axis patterning in the early mouse embryo
SJ Arnold, EJ Robertson - Nature reviews Molecular cell biology, 2009 - nature.com
Genetic studies have identified the key signalling pathways and developmentally regulated
transcription factors that govern cell lineage allocation and axis patterning in the early …
transcription factors that govern cell lineage allocation and axis patterning in the early …
[HTML][HTML] Autophagy influences glomerular disease susceptibility and maintains podocyte homeostasis in aging mice
…, T Wiech, F Grahammer, SJ Arnold… - The Journal of …, 2010 - Am Soc Clin Investig
Injury and loss of podocytes are leading factors of glomerular disease and renal failure. The
postmitotic podocyte is the primary glomerular target for toxic, immune, metabolic, and …
postmitotic podocyte is the primary glomerular target for toxic, immune, metabolic, and …
Pluripotency factors regulate definitive endoderm specification through eomesodermin
Understanding the molecular mechanisms controlling early cell fate decisions in mammals
is a major objective toward the development of robust methods for the differentiation of …
is a major objective toward the development of robust methods for the differentiation of …
The T-box transcription factor Eomes/Tbr2 regulates neurogenesis in the cortical subventricular zone
SJ Arnold, GJ Huang, AFP Cheung, T Era… - Genes & …, 2008 - genesdev.cshlp.org
The embryonic subventricular zone (SVZ) is a critical site for generating cortical projection
neurons; however, molecular mechanisms regulating neurogenesis specifically in the SVZ are …
neurons; however, molecular mechanisms regulating neurogenesis specifically in the SVZ are …
[HTML][HTML] Brachyury is a target gene of the Wnt/β-catenin signaling pathway
SJ Arnold, J Stappert, A Bauer, A Kispert… - Mechanisms of …, 2000 - Elsevier
To identify target genes of the Wnt/β-catenin signaling pathway in early mouse embryonic
development we have established a co-culture system consisting of NIH3T3 fibroblasts …
development we have established a co-culture system consisting of NIH3T3 fibroblasts …
Pivotal roles for eomesodermin during axis formation, epithelium-to-mesenchyme transition and endoderm specification in the mouse
SJ Arnold, UK Hofmann, EK Bikoff, EJ Robertson - 2008 - journals.biologists.com
The T-box transcription factor eomesodermin (Eomes) has been implicated as an important
component in germ layer induction and patterning in vertebrate embryos. In the mouse, …
component in germ layer induction and patterning in vertebrate embryos. In the mouse, …
The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation
…, S Dräger, EK Bikoff, EJ Robertson, SJ Arnold - Nature cell …, 2011 - nature.com
Instructive programmes guiding cell-fate decisions in the developing mouse embryo are
controlled by a few so-termed master regulators. Genetic studies demonstrate that the T-box …
controlled by a few so-termed master regulators. Genetic studies demonstrate that the T-box …
Cortical and clonal contribution of Tbr2 expressing progenitors in the developing mouse brain
The individual contribution of different progenitor subtypes towards the mature rodent
cerebral cortex is not fully understood. Intermediate progenitor cells (IPCs) are key to …
cerebral cortex is not fully understood. Intermediate progenitor cells (IPCs) are key to …
[HTML][HTML] Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo
SJ Arnold, S Maretto, A Islam, EK Bikoff… - Developmental …, 2006 - Elsevier
Three closely related mammalian R-Smads, namely Smad1, Smad5 and Smad8, are
activated by BMP receptors. Here we have taken a genetic approach to further dissect their …
activated by BMP receptors. Here we have taken a genetic approach to further dissect their …