User profiles for Sebastian Lickert
Dr. sc. ETH Sebastian LickertLaboratory of Applied Mechanobiology, ETH Zurich Verified email at hest.ethz.ch Cited by 136 |
Site-Specifically-Labeled Antibodies for Super-Resolution Microscopy Reveal In Situ Linkage Errors
SM Früh, U Matti, PR Spycher, M Rubini, S Lickert… - ACS …, 2021 - ACS Publications
The precise spatial localization of proteins in situ by super-resolution microscopy (SRM)
demands their targeted labeling. Positioning reporter molecules as close as possible to the …
demands their targeted labeling. Positioning reporter molecules as close as possible to the …
Platelets drive fibronectin fibrillogenesis using integrin αIIbβ3
Platelets interact with multiple adhesion proteins during thrombogenesis, yet little is known
about their ability to assemble fibronectin matrix. In vitro three-dimensional superresolution …
about their ability to assemble fibronectin matrix. In vitro three-dimensional superresolution …
Nanoconfinement of microvilli alters gene expression and boosts T cell activation
T cells sense and respond to their local environment at the nanoscale by forming small actin-rich
protrusions, called microvilli, which play critical roles in signaling and antigen …
protrusions, called microvilli, which play critical roles in signaling and antigen …
[HTML][HTML] Morphometric analysis of spread platelets identifies integrin αIIbβ3-specific contractile phenotype
Haemostatic platelet function is intimately linked to cellular mechanics and cytoskeletal
morphology. How cytoskeletal reorganizations give rise to a highly contractile phenotype that is …
morphology. How cytoskeletal reorganizations give rise to a highly contractile phenotype that is …
Contractility defects hinder GPVI-mediated platelet activation and affect platelet functions beyond clot contraction
…, R Fisher, R Alsufyani, S Lickert… - … and Practice in …, 2024 - centaur.reading.ac.uk
Background: Active and passive biomechanical properties of platelets contribute substantially
to thrombus formation. Actomyosin contractility drives clot contraction required for …
to thrombus formation. Actomyosin contractility drives clot contraction required for …
[HTML][HTML] Contractility defects hinder glycoprotein VI-mediated platelet activation and affect platelet functions beyond clot contraction
…, N Lakic, R Fisher, R Alsufyani, S Lickert… - Research and Practice …, 2024 - Elsevier
Background Active and passive biomechanical properties of platelets contribute substantially
to thrombus formation. Actomyosin contractility drives clot contraction required for …
to thrombus formation. Actomyosin contractility drives clot contraction required for …
Nanofilms produced by magnetron enhanced plasma polymerization from methane and oxygen for coating of rigid contact lenses
…, L Ledernez, G Dame, S Lickert… - Plasma Processes …, 2013 - Wiley Online Library
Although soft contact lenses are more widespread, rigid contact lenses have been around
for decades and their materials have been greatly improved, especially in terms of oxygen …
for decades and their materials have been greatly improved, especially in terms of oxygen …
Platelets exploit fibrillar adhesions to assemble fibronectin matrix revealing new force-regulated thrombus remodeling mechanisms
Upon vascular injury, platelets are crucial for thrombus formation and contraction, but do
they directly initiate early tissue repair processes? Using 3D super-resolution microscopy, …
they directly initiate early tissue repair processes? Using 3D super-resolution microscopy, …
Nanoporous Substrates to Advance CAR-T Cell Production for Advanced Cell Therapies
T Zünd, S Lickert, A Strebel, M Murner, T Willms… - Blood, 2023 - Elsevier
Background: CAR-T cell therapy has transformed blood cancer treatment with promising
clinical trial outcomes. However, access to this therapy has been limited due lengthy and …
clinical trial outcomes. However, access to this therapy has been limited due lengthy and …
Impact of Recombinant Factor VIII and Platelet Interaction on Platelet Functionality and Hemophilia a Treatment
Background: Platelets play an important role throughout the various stages of hemostasis.
After vascular injury, platelets become activated in a pro-aggregatory state, and subsequently …
After vascular injury, platelets become activated in a pro-aggregatory state, and subsequently …