Inhibiting interleukin 36 receptor signaling reduces fibrosis in mice with chronic intestinal inflammation
…, J Zheng, P Baum, S Meyer, S Schürmann… - Gastroenterology, 2019 - Elsevier
Background & Aims Intestinal fibrosis is a long-term complication in inflammatory bowel
diseases (IBD) that frequently results in functional damage, bowel obstruction, and surgery. …
diseases (IBD) that frequently results in functional damage, bowel obstruction, and surgery. …
Label‐free multiphoton endomicroscopy for minimally invasive in vivo imaging
…, M Waldner, O Friedrich, S Schürmann - Advanced …, 2019 - Wiley Online Library
Multiphoton microscopy of cellular autofluorescence and second harmonic generation from
collagen facilitates imaging of living cells and tissues without the need for additional …
collagen facilitates imaging of living cells and tissues without the need for additional …
[HTML][HTML] Beyond endoscopic assessment in inflammatory bowel disease: real-time histology of disease activity by non-linear multimodal imaging
Assessing disease activity is a prerequisite for an adequate treatment of inflammatory bowel
diseases (IBD) such as Crohn’s disease and ulcerative colitis. In addition to endoscopic …
diseases (IBD) such as Crohn’s disease and ulcerative colitis. In addition to endoscopic …
[HTML][HTML] Early signs of architectural and biomechanical failure in isolated myofibers and immortalized myoblasts from desmin-mutant knock-in mice
…, C Pollmann, B Reischl, A Buttgereit, S Schürmann… - Scientific reports, 2017 - nature.com
In striated muscle, desmin intermediate filaments interlink the contractile myofibrillar apparatus
with mitochondria, nuclei, and the sarcolemma. The desmin network’s pivotal role in …
with mitochondria, nuclei, and the sarcolemma. The desmin network’s pivotal role in …
[PDF][PDF] Second harmonic generation microscopy probes different states of motor protein interaction in myofibrils
S Schürmann, F Von Wegner, RHA Fink, O Friedrich… - Biophysical journal, 2010 - cell.com
The second harmonic generation (SHG) signal intensity sourced from skeletal muscle myosin
II strongly depends on the polarization of the incident laser beam relative to the muscle …
II strongly depends on the polarization of the incident laser beam relative to the muscle …
[PDF][PDF] Estimating the 3D pore size distribution of biopolymer networks from directionally biased data
The pore size of biopolymer networks governs their mechanical properties and strongly
impacts the behavior of embedded cells. Confocal reflection microscopy and second harmonic …
impacts the behavior of embedded cells. Confocal reflection microscopy and second harmonic …
Políticas TIC en educación en América Latina: más allá del modelo 1: 1
MT Lugo, VE Kelly, S Schurmann - Campus Virtuales, 2015 - uajournals.com
El artículo presenta un estado de situación de las políticas de integración de TIC en los
sistemas educativos de América Latina a partir de relevamientos recientes realizados por …
sistemas educativos de América Latina a partir de relevamientos recientes realizados por …
[HTML][HTML] Interferon regulatory factor 1 (IRF-1) promotes intestinal group 3 innate lymphoid responses during Citrobacter rodentium infection
…, T Leupold, L Kreiss, M Waldner, S Schürmann… - Nature …, 2022 - nature.com
Group 3 innate lymphoid cells (ILC3s) are crucial mediators of immunity and epithelial
barrier function during immune responses against extracellular bacteria. Here, we identify …
barrier function during immune responses against extracellular bacteria. Here, we identify …
Mechano-regulation of the beating heart at the cellular level–mechanosensitive channels in normal and diseased heart
O Friedrich, S Wagner, AR Battle, S Schürmann… - Progress in biophysics …, 2012 - Elsevier
The heart as a contractile hollow organ finely tunes mechanical parameters such as stroke
volume, stroke pressure and cardiac output according to filling volumes, filling pressures via …
volume, stroke pressure and cardiac output according to filling volumes, filling pressures via …
[HTML][HTML] Natural NADH and FAD autofluorescence as label-free biomarkers for discriminating subtypes and functional states of immune cells
…, O Friedrich, MF Neurath, S Schürmann… - International journal of …, 2022 - mdpi.com
Immune cell activity is a major factor for disease progression in inflammatory bowel diseases
(IBD). Classifying the type and functional state of immune cells is therefore crucial in clinical …
(IBD). Classifying the type and functional state of immune cells is therefore crucial in clinical …