Neural induction in vertebrates generates a CNS that extends the rostral-caudal length of
the body. The prevailing view is that neural cells are initially induced with anterior (forebrain) …

ChIP-seq has become a widely adopted genomic assay in recent years to determine binding
sites for transcription factors or enrichments for specific histone modifications. Beside …

RNA-binding proteins (RBPs) play diverse roles in regulating co-transcriptional RNA-processing
and chromatin functions, but our knowledge of the repertoire of chromatin-associated …

Non-negative matrix factorization (NMF) has been widely used for the analysis of genomic
data to perform feature extraction and signature identification due to the interpretability of the …

We show how residual stresses emerge in a visco-elastic material as a signature of its past
flow history, through an interplay between flow-modified microscopic relaxation and …

Robotic process automation (RPA) and artificial intelligence (AI) have traditionally been
viewed as separate and somewhat unequal worlds—RPA proponents consider AI to be …

Today’s production, distribution, and uses of electricity, in spite of significant improvements
in efficiency, would be familiar to Tesla and Westinghouse. By contrast, the possibilities and …

Metazoans are crucially dependent on multiple layers of gene regulatory mechanisms which
allow them to control gene expression across developmental stages, tissues and cell types. …

Transcription factors (TFs) regulate gene expression by recognising and binding specific
DNA sequences. At times, these regulatory elements may be occluded by nucleosomes, …

The embryonic progression from naïve to primed pluripotency is accompanied by the rapid
decay of pluripotency-associated mRNAs and a concomitant radical morphogenetic …