User profiles for Sebastien Foulqier
Sébastien FoulquierMaastricht University - Cardiovascular Research Institute Maastricht Verified email at maastrichtuniversity.nl Cited by 879 |
WNT signaling in cardiac and vascular disease
S Foulquier, EP Daskalopoulos, G Lluri… - Pharmacological …, 2018 - ASPET
WNT signaling is an elaborate and complex collection of signal transduction pathways mediated
by multiple signaling molecules. WNT signaling is critically important for developmental …
by multiple signaling molecules. WNT signaling is critically important for developmental …
[HTML][HTML] AT2 Receptor and Tissue Injury: Therapeutic Implications
P Namsolleck, C Recarti, S Foulquier… - Current hypertension …, 2014 - Springer
The renin-angiotensin system (RAS) plays an important role in the initiation and progression
of tissue injuries in the cardiovascular and nervous systems. The detrimental actions of the …
of tissue injuries in the cardiovascular and nervous systems. The detrimental actions of the …
[HTML][HTML] Vessel-associated immune cells in cerebrovascular diseases: from perivascular macrophages to vessel-associated microglia
…, T Mizuno, HWM Steinbusch, S Foulquier - Frontiers in …, 2019 - frontiersin.org
Cerebral small vessels feed and protect the brain parenchyma thanks to the unique features
of the blood–brain barrier. Cerebrovascular dysfunction is therefore seen as a detrimental …
of the blood–brain barrier. Cerebrovascular dysfunction is therefore seen as a detrimental …
[HTML][HTML] Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood–brain barrier impairment
…, Z Ahmed, WM Blankesteijn, S Foulquier - Acta neuropathologica …, 2023 - Springer
Cerebral small vessel disease is characterised by decreased cerebral blood flow and blood–brain
barrier impairments which play a key role in the development of white matter lesions. …
barrier impairments which play a key role in the development of white matter lesions. …
[HTML][HTML] Pharmacological depletion of microglia and perivascular macrophages prevents Vascular Cognitive Impairment in Ang II-induced hypertension
…, EA Biessen, RJ van Oostenbrugge, S Foulquier - Theranostics, 2020 - ncbi.nlm.nih.gov
Rationale: Hypertension is a major risk factor for cerebral small vessel disease, the most
prevalent cause of vascular cognitive impairment. As we have shown, hypertension induced by …
prevalent cause of vascular cognitive impairment. As we have shown, hypertension induced by …
Hypertension-induced cognitive impairment: insights from prolonged angiotensin II infusion in mice
The causal relation between hypertension and cerebral small vessel disease (cSVD) remains
elusive, and appropriate animal models are scarce. We aimed to assess the relevance of …
elusive, and appropriate animal models are scarce. We aimed to assess the relevance of …
[HTML][HTML] Combined angiotensin receptor modulation in the management of cardio-metabolic disorders
Cardiovascular and metabolic disorders, such as hypertension, insulin resistance, dyslipidemia
or obesity are linked with chronic low-grade inflammation and dysregulation of the renin–…
or obesity are linked with chronic low-grade inflammation and dysregulation of the renin–…
[HTML][HTML] A systematic review of WNT signaling in endothelial cell oligodendrocyte interactions: potential relevance to cerebral small vessel disease
Key pathological features of cerebral small vessel disease (cSVD) include impairment of the
blood brain barrier (BBB) and the progression of white matter lesions (WMLs) amongst …
blood brain barrier (BBB) and the progression of white matter lesions (WMLs) amongst …
[HTML][HTML] Methylglyoxal, a highly reactive dicarbonyl compound, as a threat for blood brain barrier integrity
E Berends, RJ van Oostenbrugge, S Foulquier… - Fluids and Barriers of …, 2023 - Springer
The brain is a highly metabolically active organ requiring a large amount of glucose. Methylglyoxal
(MGO), a by-product of glucose metabolism, is known to be involved in microvascular …
(MGO), a by-product of glucose metabolism, is known to be involved in microvascular …
[HTML][HTML] The AT1/AT2 Receptor Equilibrium Is a Cornerstone of the Regulation of the Renin Angiotensin System beyond the Cardiovascular System
M Colin, C Delaitre, S Foulquier, F Dupuis - Molecules, 2023 - mdpi.com
The AT 1 receptor has mainly been associated with the pathological effects of the renin-angiotensin
system (RAS) (eg, hypertension, heart and kidney diseases), and constitutes a major …
system (RAS) (eg, hypertension, heart and kidney diseases), and constitutes a major …