Association of a Functional Deficit of the BK Ca Channel, a Synaptic Regulator of Neuronal Excitability, With Autism and Mental Retardation

…, M Elia, V Romano, S Holbert… - American Journal of …, 2006 - Am Psychiatric Assoc
Objective: Autism is a complex, largely genetic psychiatric disorder. In the majority of cases,
the cause of autism is not known, but there is strong evidence for a genetic etiology. To …

The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis

S Holbert, I Denghien, T Kiechle… - Proceedings of the …, 2001 - National Acad Sciences
Huntington's disease (HD) is a neurodegenerative disease caused by polyglutamine expansion
in the protein huntingtin (htt). Pathogenesis in HD appears to involve the formation of …

[PDF][PDF] KIF1A, an axonal transporter of synaptic vesicles, is mutated in hereditary sensory and autonomic neuropathy type 2

…, V Lavastre, M Shekarabi, S Holbert… - The American Journal of …, 2011 - cell.com
Hereditary sensory and autonomic neuropathy type II (HSANII) is a rare autosomal-recessive
disorder characterized by peripheral nerve degeneration resulting in a severe distal …

Sirtuin inhibition protects from the polyalanine muscular dystrophy protein PABPN1

…, MY Pasco, A Abu-Baker, S Holbert… - Human molecular …, 2008 - academic.oup.com
Oculopharyngeal muscular dystrophy (OPMD) is caused by polyalanine expansion in
nuclear protein PABPN1 [poly(A) binding protein nuclear 1] and characterized by muscle …

[HTML][HTML] Ulvan from Ulva armoricana (Chlorophyta) activates the PI3K/Akt signalling pathway via TLR4 to induce intestinal cytokine production

M Berri, M Olivier, S Holbert, J Dupont, H Demais… - Algal research, 2017 - Elsevier
The biological activities of water-soluble sulfated polysaccharides of green algae (ulvans)
have been explored for use as bioactive molecules for the benefit of human and animal health…

[HTML][HTML] Experimental infection of cattle with Mycobacterium tuberculosis isolates shows the attenuation of the human tubercle bacillus for cattle

B Villarreal-Ramos, S Berg, A Whelan, S Holbert… - Scientific Reports, 2018 - nature.com
The Mycobacterium tuberculosis complex (MTBC) is the collective term given to the group of
bacteria that cause tuberculosis (TB) in mammals. It has been reported that M. tuberculosis …

Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease

S Holbert, A Dedeoglu, S Humbert… - Proceedings of the …, 2003 - National Acad Sciences
Huntington's disease (HD) is a neurodegenerative disease caused by polyglutamine (polyQ)
expansion in the protein huntingtin (htt). Pathogenesis in HD seems to involve the …

[HTML][HTML] An Updated View on the Rck Invasin of Salmonella: Still Much to Discover

J Mambu, I Virlogeux-Payant, S Holbert… - Frontiers in Cellular …, 2017 - frontiersin.org
Salmonella is a facultative intracellular Gram-negative bacterium, responsible for a wide
range of food- and water-borne diseases ranging from gastroenteritis to typhoid fever …

Evaluation of mycobacteria-specific gamma interferon and antibody responses before and after a single intradermal skin test in cattle naturally exposed to M. avium …

…, S Van Der Heyden, S Holbert… - Veterinary immunology …, 2018 - Elsevier
This study reports on the diagnostic potential of IFN-γ release assays and serology for
Mycobacterium bovis in six naturally M. avium subsp. paratuberculosis (Map) exposed bulls of …

CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity

M Arango, S Holbert, D Zala, E Brouillet… - Journal of …, 2006 - Soc Neuroscience
Transcriptional dysregulation caused by expanded polyglutamines (polyGlns) in huntingtin (htt)
may be central to cell-autonomous mechanisms for neuronal cell death in Huntington's …