User profiles for Seetha Krishnan

Seetha Krishnan

University of Chicago
Verified email at uchicago.edu
Cited by 308

[HTML][HTML] Reward expectation extinction restructures and degrades CA1 spatial maps through loss of a dopaminergic reward proximity signal

S Krishnan, C Heer, C Cherian, MEJ Sheffield - Nature communications, 2022 - nature.com
Hippocampal place cells support reward-related spatial memories by forming a cognitive map
that over-represents reward locations. The strength of these memories is modulated by the …

[HTML][HTML] A thalamic-hippocampal CA1 signal for contextual fear memory suppression, extinction, and discrimination

HC Ratigan, S Krishnan, S Smith… - Nature …, 2023 - nature.com
The adaptive regulation of fear memories is a crucial neural function that prevents inappropriate
fear expression. Fear memories can be acquired through contextual fear conditioning (…

[HTML][HTML] The right dorsal habenula limits attraction to an odor in zebrafish

S Krishnan, AS Mathuru, C Kibat, M Rahman… - Current Biology, 2014 - cell.com
Background The habenula consists of an evolutionarily conserved set of nuclei that control
neuromodulator release. In lower vertebrates, the dorsal habenula receives innervation from …

Research culture: Surveying the experience of postdocs in the United States before and during the COVID-19 pandemic

A Morin, BA Helling, S Krishnan, LE Risner, ND Walker… - Elife, 2022 - elifesciences.org
In the interest of advocating for the postdoctoral community in the United States (US), we
compared the results of surveys of postdocs carried out in 2019 and in late 2020. We found that …

[HTML][HTML] Optical inhibition of larval zebrafish behaviour with anion channelrhodopsins

GA Mohamed, RK Cheng, J Ho, S Krishnan… - BMC biology, 2017 - Springer
Background Optical silencing of activity provides a way to test the necessity of neurons in
behaviour. Two light-gated anion channels, GtACR1 and GtACR2, have recently been shown …

[HTML][HTML] Activation and inhibition of tph2 serotonergic neurons operate in tandem to influence larval zebrafish preference for light over darkness

RK Cheng, S Krishnan, S Jesuthasan - Scientific reports, 2016 - nature.com
Serotonergic neurons have been implicated in a broad range of processes, but the principles
underlying their effects remain a puzzle. Here, we ask how these neurons influence the …

Neural correlates of state transitions elicited by a chemosensory danger cue

S Jesuthasan, S Krishnan, RK Cheng… - Progress in Neuro …, 2021 - Elsevier
Background Detection of predator cues changes the brain state in prey species and helps
them avoid danger. Dysfunctionality in changing the central state appropriately in stressful …

[HTML][HTML] Characterization of a thalamic nucleus mediating habenula responses to changes in ambient illumination

RK Cheng, S Krishnan, Q Lin, C Kibat, S Jesuthasan - BMC biology, 2017 - Springer
Background Neural activity in the vertebrate habenula is affected by ambient illumination. The
nucleus that links photoreceptor activity with the habenula is not well characterized. Here, …

Place conditioning in humans: opportunities for translational research

S Krishnan, RA Bevins, H de Wit - Psychopharmacology, 2023 - Springer
Rationale Translational research, especially research that bridges studies with humans and
nonhuman species, is critical to advancing our understanding of human disorders such as …

[HTML][HTML] A toxicogenomic approach for the risk assessment of the food contaminant acetamide

…, ME Andersen, PD McMullen, S Krishnan… - Toxicology and applied …, 2020 - Elsevier
Acetamide (CAS 60-35-5) is detected in common foods. Chronic rodent bioassays led to its
classification as a group 2B possible human carcinogen due to the induction of liver tumors …