The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
disease coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and deaths …

Hepatitis C virus subverts liver-specific microRNA, miR-122, to upregulate viral RNA abundance
in both infected cultured cells and in the liver of infected chimpanzees. These findings …

Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family. Although ZIKV infection
is typically mild and self-limiting in healthy adults, infection has been associated with …

Virion assembly is an important step in the life cycle of all viruses. For viruses of the Flavivirus
genus, a group of enveloped positive-sense RNA viruses, the assembly step represents …

Viruses compartmentalize their replication and assembly machinery to both evade detection
and concentrate the viral proteins and nucleic acids necessary for genome replication and …

MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression at the post-transcriptional
level. Through this activity, they are implicated in almost every cellular …

By the analysis of thermodynamic RNA secondary structure predictions, we previously
obtained evidence for evolutionarily conserved large-scale ordering of RNA virus genomes (P. …

RNA–protein interactions are central to biological regulation. Cross-linking
immunoprecipitation (CLIP)-seq is a powerful tool for genome-wide interrogation of RNA–protein …

… Selena M Sagan Selena M Sagan … One microliter of 2 M NaOH was then added to each
reaction at 95C for 5 min and reactions were stopped by addition of 2 μl formamide loading dye (…

A central hallmark of cancer cells is the reprogramming of cellular metabolism to meet the
bioenergetic and biosynthetic demands of malignant growth. Here, we report that the miR-17∼…