[HTML][HTML] Targeting DNA damage response and replication stress in pancreatic cancer
…, EM Lampraki, E Dray, B Serrels, G Caligiuri, S Rebus… - Gastroenterology, 2021 - Elsevier
Background and aims Continuing recalcitrance to therapy cements pancreatic cancer (PC)
as the most lethal malignancy, which is set to become the second leading cause of cancer …
as the most lethal malignancy, which is set to become the second leading cause of cancer …
[PDF][PDF] HNF4A and GATA6 loss reveals therapeutically actionable subtypes in pancreatic cancer
…, B McDade, D McElroy, D Ramsay, S Rebus… - Cell reports, 2020 - cell.com
Pancreatic ductal adenocarcinoma (PDAC) can be divided into transcriptomic subtypes with
two broad lineages referred to as classical (pancreatic) and squamous. We find that these …
two broad lineages referred to as classical (pancreatic) and squamous. We find that these …
Gene expression profiling of the preclinical scrapie-infected hippocampus
AR Brown, S Rebus, CS McKimmie… - Biochemical and …, 2005 - Elsevier
The molecular events that underlie prion disease neuropathology remain poorly defined.
Within the hippocampus of the ME7/CV mouse scrapie model, profound CA1 neuronal loss …
Within the hippocampus of the ME7/CV mouse scrapie model, profound CA1 neuronal loss …
Hepatitis C quantification and sequencing in blood products, haemophiliacs, and drug users
P Simmonds, S Rebus, GH Leadbetter, JF Peutherer… - The Lancet, 1990 - Elsevier
The polymerase chain reaction (PCR) detected specific hepatitis C viral (HCV) RNA
sequences in plasma from 15 of 21 haemophiliacs (12 HCV-antibody positive) and 7 of 27 …
sequences in plasma from 15 of 21 haemophiliacs (12 HCV-antibody positive) and 7 of 27 …
[PDF][PDF] Genomic and molecular analyses identify molecular subtypes of pancreatic cancer recurrence
…, EA Musgrove, D Ramsay, L Evers, S Rebus… - Gastroenterology, 2022 - Elsevier
A list of contributors will be published in full upon acceptance of the manuscript. We thank
William Shen*, Antonio Pea*, Alessandra Pulvirenti*, all the members and administrative staff …
William Shen*, Antonio Pea*, Alessandra Pulvirenti*, all the members and administrative staff …
Use of several second generation serological assays to determine the true prevalence of hepatitis C virus infection in haemophiliacs treated with non‐virus inactivated …
HG Watson, CA Ludlam, S Rebus… - British journal of …, 1992 - Wiley Online Library
To investigate the prevalence of hepatitis C virus infection in two risk groups, stored serum
samples from treated haemophiliacs and intravenous drug users were tested for anti‐HCV by …
samples from treated haemophiliacs and intravenous drug users were tested for anti‐HCV by …
[HTML][HTML] Disruption of the pro-oncogenic c-RAF–PDE8A complex represents a differentiated approach to treating KRAS–c-RAF dependent PDAC
…, N Phanthaphol, T Mcskimming, K Herbert, S Rebus… - Scientific Reports, 2024 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is considered the third leading cause of cancer
mortality in the western world, offering advanced stage patients with few viable treatment …
mortality in the western world, offering advanced stage patients with few viable treatment …
Inducible cytokine gene expression in the brain in the ME7/CV mouse model of scrapie is highly restricted, is at a strikingly low level relative to the degree of gliosis …
AR Brown, J Webb, S Rebus… - Journal of general …, 2003 - microbiologyresearch.org
The temporal course of cerebral cytokine gene expression was investigated in the ME7/CV
murine scrapie model to determine any association with neuropathological events. Analysis …
murine scrapie model to determine any association with neuropathological events. Analysis …
CXCL8 expression is associated with advanced stage, right sidedness, and distinct histological features of colorectal cancer
…, HC van Wyk, D Chang, S Rebus… - The Journal of …, 2022 - Wiley Online Library
CXCL8 is an inflammatory chemokine elevated in the colorectal cancer (CRC) tumour
microenvironment. CXCR2, the major receptor for CXCL8, is predominantly expressed by …
microenvironment. CXCR2, the major receptor for CXCL8, is predominantly expressed by …
[HTML][HTML] JAK/STAT3 represents a therapeutic target for colorectal cancer patients with stromal-rich tumors
…, J Hay, D Andersen, C Nixon, S Rebus… - Journal of Experimental …, 2024 - Springer
Colorectal cancer (CRC) is a heterogenous malignancy underpinned by dysregulation of
cellular signaling pathways. Previous literature has implicated aberrant JAK/STAT3 signal …
cellular signaling pathways. Previous literature has implicated aberrant JAK/STAT3 signal …