User profiles for Sema Elif Eski

Sema Elif Eski

Université Libre de Bruxelles
Verified email at ulb.ac.be
Cited by 128

[HTML][HTML] Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

…, G Doumont, P Gillotay, XH Liao, SE Eski… - Nature …, 2022 - nature.com
The thyroid gland captures iodide in order to synthesize hormones that act on almost all
tissues and are essential for normal growth and metabolism. Low plasma levels of thyroid …

A single-cell atlas of de novo β-cell regeneration reveals the contribution of hybrid β/δ-cells to diabetes recovery in zebrafish

…, M Kamel, LD Silva, B Spanjaard, SE Eski… - …, 2022 - journals.biologists.com
Regeneration-competent species possess the ability to reverse the progression of severe
diseases by restoring the function of the damaged tissue. However, the cellular dynamics …

Single‐cell transcriptome analysis reveals thyrocyte diversity in the zebrafish thyroid gland

P Gillotay, M Shankar, B Haerlingen, SE Eski… - EMBO …, 2020 - embopress.org
The thyroid gland regulates growth and metabolism via production of thyroid hormone in
follicles composed of thyrocytes. So far, thyrocytes have been assumed to be a homogenous …

Purinergic signalling selectively modulates maintenance but not repair neurogenesis in the zebrafish olfactory epithelium

…, U Sakizli, B Bali, Y Kocagöz, SE Eski… - The FEBS …, 2020 - Wiley Online Library
Olfactory sensory neurons (OSNs) of the vertebrate olfactory epithelium (OE) undergo
continuous turnover but also regenerate efficiently when the OE is acutely damaged by traumatic …

Keratin filaments mediate the expansion of extra‐embryonic membranes in the post‐gastrulation mouse embryo

W Nahaboo, SE Eski, E Despin‐Guitard… - The EMBO …, 2022 - embopress.org
Mesoderm arises at gastrulation and contributes to both the mouse embryo proper and its
extra‐embryonic membranes. Two‐photon live imaging of embryos bearing a keratin reporter …

[HTML][HTML] Single-Cell Trajectory Inference Guided Enhancement of Thyroid Maturation In Vitro Using TGF-Beta Inhibition

M Romitti, SE Eski, BF Fonseca, P Gillotay… - Frontiers in …, 2021 - frontiersin.org
The thyroid gland regulates metabolism and growth via secretion of thyroid hormones by
thyroid follicular cells (TFCs). Loss of TFCs, by cellular dysfunction, autoimmune destruction or …

[HTML][HTML] CD38 promotes hematopoietic stem cell dormancy

L Ibneeva, SP Singh, A Sinha, SE Eski, R Wehner… - PLoS …, 2024 - journals.plos.org
A subpopulation of deeply quiescent, so-called dormant hematopoietic stem cells (dHSCs)
resides at the top of the hematopoietic hierarchy and serves as a reserve pool for HSCs. The …

Asymmetry in the frequency and position of mitosis in the mouse embryo epiblast at gastrulation

…, E Despin‐Guitard, M Stower, W Nahaboo, SE Eski… - EMBO …, 2020 - embopress.org
At gastrulation, a subpopulation of epiblast cells constitutes a transient posteriorly located
structure called the primitive streak, where cells that undergo epithelial–mesenchymal …

Disparate progenitor cell populations contribute to maintenance and repair neurogenesis in the zebrafish olfactory epithelium

Y Kocagöz, MC Demirler, SE Eski, K Güler… - Cell and tissue …, 2022 - Springer
Olfactory sensory neurons (OSNs) undergo constant turnover under physiological conditions
but also regenerate efficiently following tissue injury. Maintenance and repair neurogenesis …

[PDF][PDF] HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes

V Vandenbempt, SE Eski, MK Brahma, A Li… - Iscience, 2024 - cell.com
An altered gut microbiota is associated with type 1 diabetes (T1D), affecting the production
of short-chain fatty acids (SCFA) and glucose homeostasis. We previously demonstrated that …