User profiles for Seong Won Cha
 | Seong Won ChaDepartment of Electrical and Computer Engineering, University of California, San Diego Verified email at ucsd.edu Cited by 1329 |
[HTML][HTML] Integrated proteogenomic characterization of human high-grade serous ovarian cancer
To provide a detailed analysis of the molecular components and underlying mechanisms
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …
associated with ovarian cancer, we performed a comprehensive mass-spectrometry-based …
[PDF][PDF] Assembling the community-scale discoverable human proteome
The increasing throughput and sharing of proteomics mass spectrometry data have now
yielded over one-third of a million public mass spectrometry runs. However, these discoveries …
yielded over one-third of a million public mass spectrometry runs. However, these discoveries …
Proteogenomic database construction driven from large scale RNA-seq data
The advent of inexpensive RNA-seq technologies and other deep sequencing technologies
for RNA has the promise to radically improve genomic annotation, providing information on …
for RNA has the promise to radically improve genomic annotation, providing information on …
Proteogenomic strategies for identification of aberrant cancer peptides using large‐scale next‐generation sequencing data
Cancer is driven by the acquisition of somatic DNA lesions. Distinguishing the early driver
mutations from subsequent passenger mutations is key to molecular subtyping of cancers, …
mutations from subsequent passenger mutations is key to molecular subtyping of cancers, …
Advanced proteogenomic analysis reveals multiple peptide mutations and complex immunoglobulin peptides in colon cancer
Aiming toward an improved understanding of the regulation of proteins in cancer, recent
studies from the Clinical Proteomic Tumor Analysis Consortium (CPTAC) have focused on …
studies from the Clinical Proteomic Tumor Analysis Consortium (CPTAC) have focused on …
Serial changes in liquid biopsy-derived variant allele frequency predict immune checkpoint inhibitor responsiveness in the pan-cancer setting
S Kato, B Li, JJ Adashek, SW Cha… - …, 2022 - Taylor & Francis
Major immunotherapy challenges include a limited number of predictive biomarkers and the
unusual imaging features post-therapy, such as pseudo-progression, which denote immune …
unusual imaging features post-therapy, such as pseudo-progression, which denote immune …
Proteogenomic annotation of Chinese hamsters reveals extensive novel translation events and endogenous retroviral elements
A high-quality genome annotation greatly facilitates successful cell line engineering.
Standard draft genome annotation pipelines are based largely on de novo gene prediction, …
Standard draft genome annotation pipelines are based largely on de novo gene prediction, …
[HTML][HTML] The antibody repertoire of colorectal cancer
Immunotherapy is becoming increasingly important in the fight against cancers, using and
manipulating the body's immune response to treat tumors. Understanding the immune …
manipulating the body's immune response to treat tumors. Understanding the immune …
[HTML][HTML] Updates on Group B Streptococcus Infection in the Field of Obstetrics and Gynecology
Group B Streptococcus (GBS, Streptococcus agalactiae) is a Gram-positive bacterium that is
commonly found in the gastrointestinal and urogenital tracts. However, its colonization …
commonly found in the gastrointestinal and urogenital tracts. However, its colonization …
Efficient molecular genetic diagnosis of enlarged vestibular aqueducts in East Asians
…, KK Nishimura, WJ Cha, MW Seong… - Genetic testing and …, 2009 - liebertpub.com
Context: Enlargement of the vestibular aqueduct (EVA) is a commonly detected inner ear
anomaly related to hearing loss and often associated with mutations of SLC26A4 encoding …
anomaly related to hearing loss and often associated with mutations of SLC26A4 encoding …