User profiles for Serena M Dudek

Serena Dudek

National Institute of Environmental Health Sciences, NIH
Verified email at niehs.nih.gov
Cited by 9575

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.

SM Dudek, MF Bear - … of the National Academy of Sciences, 1992 - National Acad Sciences
We tested a theoretical prediction that patterns of excitatory input activity that consistently
fail to activate target neurons sufficiently to induce synaptic potentiation will instead cause a …

Cortico-striatal synaptic defects and OCD-like behaviours in Sapap3-mutant mice

…, C Feliciano, M Chen, JP Adams, J Luo, SM Dudek… - Nature, 2007 - nature.com
… l, m, Field recordings from infected striatal areas of P21–P25 … (m). P < 0.001, repeated
measures ANOVA for l; *P < 0.05, two-tailed t-test for m; n is 12 and 10 for l, and 10 and 9 for m for …

Bidirectional long-term modification of synaptic effectiveness in the adult and immature hippocampus

SM Dudek, MF Bear - Journal of Neuroscience, 1993 - Soc Neuroscience
Previously we showed that delivering 900 pulses to the Schaffer collateral-CA1 pathway at 1–3
Hz causes a lasting depression of synaptic effectiveness that is input specific and …

Common forms of synaptic plasticity in the hippocampus and neocortex in vitro

A Kirkwood, SM Dudek, JT Gold, CD Aizenman… - Science, 1993 - science.org
Activity-dependent synaptic plasticity in the superficial layers of juvenile cat and adult rat
visual neocortex was compared with that in adult rat hippocampal field CA1. Stimulation of …

[PDF][PDF] Different neuronal activity patterns induce different gene expression programs

…, JM Ward, ML Andermann, RN Saha, SM Dudek… - Neuron, 2018 - cell.com
A vast number of different neuronal activity patterns could each induce a different set of
activity-regulated genes. Mapping this coupling between activity pattern and gene induction …

Rediscovering area CA2: unique properties and functions

SM Dudek, GM Alexander, S Farris - Nature Reviews Neuroscience, 2016 - nature.com
Hippocampal area CA2 has several features that distinguish it from CA1 and CA3, including
a unique gene expression profile, failure to display long-term potentiation and relative …

Perineuronal nets suppress plasticity of excitatory synapses on CA2 pyramidal neurons

…, L Pozzo-Miller, RJ Weinberg, SM Dudek - Journal of …, 2016 - Soc Neuroscience
Long-term potentiation of excitatory synapses on pyramidal neurons in the stratum radiatum
rarely occurs in hippocampal area CA2. Here, we present evidence that perineuronal nets (…

Synapse elimination accompanies functional plasticity in hippocampal neurons

…, JM Reece, A Jeromin, SM Dudek - Proceedings of the …, 2008 - National Acad Sciences
A critical component of nervous system development is synapse elimination during early
postnatal life, a process known to depend on neuronal activity. Changes in synaptic strength in …

RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory

…, KJ Ressler, SM Dudek… - Proceedings of the …, 2010 - National Acad Sciences
Learning and memory have been closely linked to strengthening of synaptic connections
between neurons (ie, synaptic plasticity) within the dentate gyrus (DG)–CA3–CA1 trisynaptic …

Role of the vasopressin 1b receptor in rodent aggressive behavior and synaptic plasticity in hippocampal area CA2

…, SK Williams Avram, DA Caruana, SM Dudek… - Molecular …, 2015 - nature.com
The vasopressin 1b receptor (Avpr1b) is critical for social memory and social aggression in
rodents, yet little is known about its specific roles in these behaviors. Some clues to Avpr1b …