User profiles for Sergii Domanskyi

Sergii Domanskyi

The Jackson Laboratory
Verified email at jax.org
Cited by 364

[HTML][HTML] Visibility graph based temporal community detection with applications in biological time series

M Zheng, S Domanskyi, C Piermarocchi, GI Mias - Scientific reports, 2021 - nature.com
Temporal behavior is an essential aspect of all biological systems. Time series have been
previously represented as networks. Such representations must address two fundamental …

Predictive design of polymer molecular weight distributions in anionic polymerization

S Domanskyi, DT Gentekos, V Privman, BP Fors - Polymer Chemistry, 2020 - pubs.rsc.org
Molecular weight distributions (MWD) have a substantial impact on a diverse set of polymer
physical and rheological properties, from processability and stiffness to many aspects of …

[HTML][HTML] Polled Digital Cell Sorter (p-DCS): Automatic identification of hematological cell types from single cell RNA-sequencing clusters

S Domanskyi, A Szedlak, NT Hawkins, J Wang… - BMC …, 2019 - Springer
Background Single cell RNA sequencing (scRNA-seq) brings unprecedented opportunities
for mapping the heterogeneity of complex cellular environments such as bone marrow, and …

[HTML][HTML] Longitudinal saliva omics responses to immune perturbation: a case study

…, LRK Rogers, S Xue, M Zheng, S Domanskyi… - Scientific Reports, 2021 - nature.com
Saliva omics has immense potential for non-invasive diagnostics, including monitoring very
young or elderly populations, or individuals in remote locations. In this study, multiple saliva …

LIF, a mitogen for choroidal endothelial cells, protects the choriocapillaris: implications for prevention of geographic atrophy

…, C Piermarocchi, S Domanskyi… - EMBO molecular …, 2022 - embopress.org
In the course of our studies aiming to discover vascular bed‐specific endothelial cell (EC)
mitogens, we identified leukemia inhibitory factor (LIF) as a mitogen for bovine choroidal EC (…

A Genomically and Clinically Annotated Patient-Derived Xenograft Resource for Preclinical Research in Non–Small Cell Lung Cancer

…, BJ Sanderson, MW Lloyd, M Chen, S Domanskyi… - Cancer research, 2022 - AACR
Patient-derived xenografts of lung cancer retain key features observed in the originating
patient tumors and show expected responses to treatment with standard-of-care agents, …

Glucose‐Triggered Insulin Release from Fe3+‐Cross‐linked Alginate Hydrogel: Experimental Study and Theoretical Modeling

S Scheja, S Domanskyi, M Gamella… - …, 2017 - Wiley Online Library
We study the mechanisms involved in the release, triggered by the application of glucose, of
insulin entrapped in Fe 3+ ‐cross‐linked alginate hydrogel particles further stabilized with a …

Biomolecular Release from Alginate‐modified Electrode Triggered by Chemical Inputs Processed through a Biocatalytic Cascade–Integration of Biomolecular …

AV Okhokhonin, S Domanskyi, Y Filipov… - …, 2018 - Wiley Online Library
Biocatalytic cascades involving more than one or two enzyme‐catalyzed step are inefficient
inside alginate hydrogel prepared on an electrode surface. The problem originates from …

Kinetic model for a threshold filter in an enzymatic system for bioanalytical and biocomputing applications

V Privman, S Domanskyi, S Mailloux… - The Journal of …, 2014 - ACS Publications
A recently experimentally observed biochemical “threshold filtering” mechanism by processes
catalyzed by the enzyme malate dehydrogenase is explained in terms of a model that …

Reaction-diffusion degradation model for delayed erosion of cross-linked polyanhydride biomaterials

S Domanskyi, KL Poetz, DA Shipp… - Physical Chemistry …, 2015 - pubs.rsc.org
We develop a theoretical model to explain the long induction interval of water intake that
precedes the onset of erosion due to degradation caused by hydrolysis in the recently …