User profiles for Sergii Kropyvko

Sergii Kropyvko

Department of Functional Genomics, Institute of Molecular Biology and Genetics NAS of …
Verified email at edu.imbg.org.ua
Cited by 228

Intersectin adaptor proteins are associated with actin-regulating protein WIP in invadopodia

T Gryaznova, S Kropyvko, M Burdyniuk, O Gubar… - Cellular signalling, 2015 - Elsevier
Invasive cancer cells form actin-rich membrane protrusions called invadopodia that
degrade extracellular matrix and facilitate cell invasion and metastasis. WIP (WASP-interacting …

WIP/ITSN1 complex is involved in cellular vesicle trafficking and formation of filopodia-like protrusions

T Gryaznova, O Gubar, M Burdyniuk, S Kropyvko… - Gene, 2018 - Elsevier
WIP (WASP interacting protein) together with N-WASP (neural Wiskott-Aldrich syndrome
protein) regulates actin polymerization that is crucial for invadopodia and filopodia formation. …

Obtaining transgenic potato plants expressing the human lactoferrin gene and analysis of their resistance to phytopathogens

A Buziashvili, L Cherednichenko, S Kropyvko… - Cytology and …, 2020 - Springer
The human lactoferrin gene was transferred into genomes of several potato (Solanum tuberosum)
cultivars of Ukrainian breeding using the Agrobacterium-mediated transformation. The …

Structural diversity and differential expression of novel human intersectin 1 isoforms

S Kropyvko, D Gerasymchuk, I Skrypkina… - Molecular biology …, 2010 - Springer
Intersectin 1 (ITSN1) is an evolutionarily conserved adaptor protein that functions in clathrin-mediated
endocytosis, cell signalling and cytoskeleton rearrangements. The ITSN1 gene …

Mammalian verprolin CR16 acts as a modulator of ITSN scaffold proteins association with actin

S Kropyvko, T Gryaznova, D Morderer… - … and biophysical research …, 2017 - Elsevier
Actin cytoskeleton rearrangements are required for normal cell functioning, and their
deregulation leads to various pathologies. Members of two mammalian protein families – ITSNs (…

The atypical Rho GTPase RhoU interacts with intersectin-2 to regulate endosomal recycling pathways

O Gubar, P Croisé, S Kropyvko… - Journal of cell …, 2020 - journals.biologists.com
Rho GTPases play a key role in various membrane trafficking processes. RhoU is an
atypical small Rho GTPase related to Rac/Cdc42, which possesses unique N- and C-terminal …

Macromolecular complexes in invadopodia formation.

S Kropyvko, T Gryaznova, O Gubar… - Biopolymers & …, 2015 - search.ebscohost.com
Aim. Invasive cancer cells form membrane protrusions, invadopodia, that degrade extracellular
matrix and facilitate cell invasion and metastasis. Invadopodia contain an actin-rich core …

[HTML][HTML] Tristetraprolin expression levels and methylation status in breast cancer

S Kropyvko, A Hubiernatorova, O Mankovska… - Gene Reports, 2023 - Elsevier
Breast cancer (BC), despite of numerous studies on it, is still one of the most common types
of cancer and remains one of the leading causes of death from malignant tumors in women. …

Tristetraproline in breast cancer: treat or trick?

…, H Anastasiia, M Oksana, S Liubov, V Nataliia, L Sergii… - bioRxiv, 2022 - biorxiv.org
Breast cancer is one of the most common types of cancer. It is very heterogeneous, hence still
complicated to diagnose despite of decades of research. Post-transcriptional regulation of …

[HTML][HTML] Molecular characterization of full-length MLV-related endogenous retrovirus ChiRV1 from the chicken, Gallus gallus

L Borysenko, V Stepanets, AV Rynditch - Virology, 2008 - Elsevier
We report the first full-length sequence of an endogenous retrovirus from the genome of
domestic chicken, that is not related to the Avian leukemia viruses (ALV). This retrovirus, …