User profiles for Seung Hyeok Han

Seung Hyeok Han

Yonsei University
Verified email at yuhs.ac
Cited by 12390

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

HM Kang, SH Ahn, P Choi, YA Ko, SH Han, F Chinga… - Nature medicine, 2015 - nature.com
Renal fibrosis is the histological manifestation of a progressive, usually irreversible process
causing chronic and end-stage kidney disease. We performed genome-wide transcriptome …

[HTML][HTML] An increase in mean platelet volume from baseline is associated with mortality in patients with severe sepsis or septic shock

…, YE Kwon, YL Kim, KS Park, HJ Ryu, JT Park, SH Han… - PloS one, 2015 - journals.plos.org
Introduction Mean platelet volume (MPV) is suggested as an index of inflammation, disease
activity, and anti-inflammatory treatment efficacy in chronic inflammatory disorders; however, …

Red blood cell distribution width is an independent predictor of mortality in acute kidney injury patients treated with continuous renal replacement therapy

…, JK Kim, DE Yoo, SJ Kim, SH Han… - Nephrology Dialysis …, 2012 - academic.oup.com
Background. A potential independent association was recently demonstrated between high
red blood cell distribution width (RDW) and the risk of all-cause mortality in patients with …

[HTML][HTML] Characterization of ferroptosis in kidney tubular cell death under diabetic conditions

S Kim, SW Kang, J Joo, SH Han, H Shin, BY Nam… - Cell Death & …, 2021 - nature.com
Kidney tubular cell death induced by transforming growth factor-β1 (TGF-β1) is known to
contribute to diabetic nephropathy, a major complication of diabetes. Caspase-3-dependent …

[HTML][HTML] An increase in red blood cell distribution width from baseline predicts mortality in patients with severe sepsis or septic shock

…, JT Park, EJ Kim, JH Han, JS Han, JY Choi, SH Han… - Critical care, 2013 - Springer
Introduction A potential independent association was recently demonstrated between high
red blood cell distribution width (RDW) and the risk of all-cause mortality in critically ill patients…

[HTML][HTML] Polypharmacy, hospitalization, and mortality risk: a nationwide cohort study

…, K Kalantar-Zadeh, EW Kang, SW Kang, SH Han - Scientific reports, 2020 - nature.com
Polypharmacy is a growing and major public health issue, particularly in the geriatric
population. This study aimed to examine the association between polypharmacy and the risk of …

Circulating α-klotho levels in CKD and relationship to progression

…, HJ Oh, TH Yoo, SW Kang, DS Han, SH Han - American Journal of …, 2013 - Elsevier
BACKGROUND: α-Klotho is reported to have protective effects against kidney injury, and its
renal expression is decreased in many experimental models of kidney disease. However, …

Preservation of renal function by thyroid hormone replacement therapy in chronic kidney disease patients with subclinical hypothyroidism

…, SJ Kim, HJ Oh, HR Kim, JH Han… - The Journal of …, 2012 - academic.oup.com
Context: Subclinical hypothyroidism is not a rare condition, but the use of thyroid hormone to
treat subclinical hypothyroidism is an issue of debate. Objective: This study was undertaken …

[HTML][HTML] Decreased circulating C3 levels and mesangial C3 deposition predict renal outcome in patients with IgA nephropathy

…, TH Yoo, SW Kang, KH Choi, HJ Jeong, SH Han - PloS one, 2012 - journals.plos.org
Background and Aims Mesangial C3 deposition is frequently observed in patients with IgA
nephropathy (IgAN). However, the role of complement in the pathogenesis or progression of …

Thyroid hormone replacement therapy attenuates the decline of renal function in chronic kidney disease patients with subclinical hypothyroidism

…, FM Doh, HM Koo, HR Kim, JH Han, JT Park, SH Han… - Thyroid, 2013 - liebertpub.com
Background: Subclinical hypothyroidism (SCH) is not a rare condition in females, the elderly,
or patients with chronic kidney disease (CKD). Even though previous studies have …