Pore-modulating toxins exploit inherent slow inactivation to block K+ channels

I Karbat, H Altman-Gueta, S Fine… - Proceedings of the …, 2019 - National Acad Sciences
Voltage-dependent potassium channels (K v s) gate in response to changes in electrical
membrane potential by coupling a voltage-sensing module with a K + -selective pore. Animal …

Reduced activity of GIRK1‐containing heterotetramers is sufficient to affect neuronal functions, including synaptic plasticity and spatial learning and memory

A Mett, I Karbat, M Tsoory, S Fine… - The Journal of …, 2021 - Wiley Online Library
Key points G‐protein inwardly rectifying K + (GIRK) channels consist of four homologous
subunits (GIRK1‐4) and are essential regulators of electrical excitability in the nervous system. …

Delivery following intracytoplasmic injection of mature sperm cells recovered by testicular fine needle aspiration in a case of hypergonadotropic azoospermia due to …

…, DB Weiss, S Friedler, I Ben-Shachar… - Human …, 1996 - academic.oup.com
… Immediately after oocyte retrieval, we proceeded with the testicular and epididymal fine … in
the aspirate, we proceeded to do testicular fine needle aspirations in various parts of the testis. …

Trimming the disordered C-terminal extension of the protease inhibitor Hg1 produces a potent Kv1. 3 blocker

C Saikia, H Altman-Gueta, S Fine, O Dym, F Frolow… - Biophysical …, 2023 - cell.com
Animal venom contains a mixture of toxic polypeptides that act in synergy to enable the fast
immobilization of prey or deter predators and competitors. This polypeptide arsenal is …

[PDF][PDF] Hetromerization of Kir Channels: Principles of Assembly and Physiological Significance

A Mett, S Fine, A Kollewe, I Karbat, B Fakler… - Biophysical …, 2020 - cell.com
G-protein coupled K+(Kir3. x) channels are unique channels that translate chemical
neurotransmission via GPCR activation to electrical signals. It generates slow postsynaptic K+ …

Putative biological mechanisms of the effect of iron deficiency on brain biochemistry and behavior

MBH Youdim, D Ben-Shachar, S Yehuda - The American journal of clinical …, 1989 - Elsevier
An animal model of nutritional iron deficiency (ID) is described that demonstrates a reduction
of brain nonheme iron. The most prominent feature of ID is the significant and selective …

Monsters, Inc.: the fightback

S Fine - The shifting border, 2020 - manchesterhive.com
… Sarah Fine begins her response by calling Ayelet Shachar's lead essay "a Leviathan for
the twenty-first century." We have become accustomed to a “traditional” picture of the modern …

Environmental effects on molecular and phenotypic variation in populations of Eruca sativa across a steep climatic gradient

E Westberg, S Ohali, A Shevelevich, P Fine… - Ecology and …, 2013 - Wiley Online Library
In I srael E ruca sativa has a geographically narrow distribution across a steep climatic gradient
that ranges from mesic Mediterranean to hot desert environments. These conditions offer …

[HTML][HTML] Apolipoprotein E Is Synthesized in the Retina by Müller Glial Cells, Secreted into the Vitreous, and Rapidly Transported into the Optic Nerve by Retinal …

…, JH Sandell, BM Schreiber, RE Fine - Journal of Biological …, 1996 - ASBMB
We have investigated the synthesis and transport of apoE, the major apolipoprotein of the
central nervous system, in the retina of the living rabbit. Four hours after the injection of [ 35 S]…

Selecting by merit

A Shachar - Migration in Political Theory, 2016 - books.google.com
… I thank Sarah Fine and Lea Ypi for their insights on this point. 8 For further discussion, see
Ayelet Shachar,“Picking Winners: Olympic Citizenship and the Global Race for Talent,” Yale …