User profiles for Shahar Bracha

Shahar Bracha

Massachusetts Institute of Technology
Verified email at mit.edu
Cited by 181

[HTML][HTML] Neuronal small RNAs control behavior transgenerationally

…, E Star, S Anava, E Azmon, M Hendricks, S Bracha… - Cell, 2019 - cell.com
It is unknown whether the activity of the nervous system can be inherited. In Caenorhabditis
elegans nematodes, parental responses can transmit heritable small RNAs that regulate …

Improving protein optimization with smoothed fitness landscapes

A Kirjner, J Yim, R Samusevich, S Bracha… - The Twelfth …, 2023 - openreview.net
The ability to engineer novel proteins with higher fitness on a given task would be revolutionary
for biotechnology and medicine. Modeling the combinatorially large space of sequences …

Engineering brain parasites for intracellular delivery of therapeutic proteins

S Bracha, K Hassi, PD Ross, S Cobb, L Sheiner… - BioRxiv, 2018 - biorxiv.org
Protein therapy has the potential to alleviate many neurological diseases; however, delivery
mechanisms for the central nervous system (CNS) are limited, and intracellular delivery …

SN 2018hmx: An Extreme Type II SN with High Nickel Mass

S Bracha - The Extragalactic Explosive Universe: the New …, 2019 - ui.adsabs.harvard.edu
We present observations of the extreme Type IIP/L SN 2018hmx. This SN reached a peak
magnitude of-19, which is very luminous for a SN II with no obvious signs of interaction and …

Prophylactic and therapeutic efficacy of human intravenous immunoglobulin in treating West Nile virus infection in mice

D Ben-Nathan, S Lustig, G Tam… - The Journal of …, 2003 - academic.oup.com
West Nile virus (WNV) is a mosquito-borne disease found most commonly in Africa, West
Asia, and the Middle East, where up to 40% of the human population possesses antibodies. It …

[HTML][HTML] Androgen receptor: a potential therapeutic target for glioblastoma

…, A Mordechai, Y Fellig, S Rabani, T Shahar… - Oncotarget, 2018 - ncbi.nlm.nih.gov
… Nomi Zalcman, # 1, 2, * Tamar Canello, # 1, 2, * Haim Ovadia, 2 Hanna Charbit, 1, 2
Bracha Zelikovitch, 1, 2 Anat Mordechai, 1, 3 Yakov Fellig, 4 Stav Rabani, 5 Tal Shahar, 5, 6 …

GENO-23AMPLIFICATION OF CHROMOSOME Xq11. 1-Xq11. 2 MIGHT PLAY A ROLE IN GLIOBLASTOMA

T Canello, T Shahar, B Zelikovitch, A Mordechai… - Neuro …, 2015 - ncbi.nlm.nih.gov
GBMs. METHODS AND RESULTS: We performed a genome-wide copy number and loss of
heterozygosity analyzed on DNA extracted from 5 formalin fixed paraffin embedded samples …

CSIG-13. Androgen receptor is involved in glioblastoma and presents a potential therapeutic target

…, A Mordechai, Y Fellig, S Rabani, T Shahar… - 2016 - academic.oup.com
To investigate genetic alterations in glioblastoma (GBM), we performed a genome-wide copy
number and loss of heterozygosity (LOH) array (OncoScan FFPE Express, Affymetrix) on …

Conflicting pathology reports: a diagnostic dilemma

T Shahar, U Rozovski, Y Shapira, E Nossek… - Journal of …, 2015 - thejns.org
The differential diagnosis of a brain lesion with two discordant pathology reports includes the
presence of collision tumor, metaplastic changes, and labeling errors that occurred during …

Control of breast cancer growth and initiation by the Stem cell–associated transcription factor TCF3

M Slyper, A Shahar, A Bar-Ziv, RZ Granit, T Hamburger… - Cancer research, 2012 - AACR
Regulatory factors controlling stem cell identity and self-renewal are often active in aggressive
cancers and are thought to promote their growth and progression. TCF3 (also known as …