User profiles for Shaik N Pasha

Shaik Naseer Pasha

Senior Scientist, Avesthagen Limited
Verified email at avesthagen.com
Cited by 282

The hypertrophic cardiomyopathy mutations R403Q and R663H increase the number of myosin heads available to interact with actin

…, DV Trivedi, MM Morck, AS Adhikari, SN Pasha… - Science …, 2020 - science.org
Hypertrophic cardiomyopathy (HCM) mutations in β-cardiac myosin and myosin binding
protein-C (MyBP-C) lead to hypercontractility of the heart, an early hallmark of HCM. We show …

Myosinome: A database of myosins from select eukaryotic genomes to facilitate analysis of sequence-structure-function relationships

…, CC Reddy, M Iftekhar, SN Pasha… - … and Biology Insights, 2012 - journals.sagepub.com
Myosins are one of the largest protein superfamilies with 24 classes. They have conserved
structural features and catalytic domains yet show huge variation at different domains …

The molecular basis of hypercontractility caused by the hypertrophic cardiomyopathy mutations R403Q and R663H

…, DV Trivedi, MM Morck, AS Adhikari, SN Pasha… - bioRxiv, 2019 - biorxiv.org
Hypertrophic cardiomyopathy (HCM) mutations in ß-cardiac myosin and myosin binding
protein-C (MyBP-C) cause hypercontractility of the heart. We show that hypercontractility caused …

Design and synthesis of imidazo [2, 1-b] thiazole linked triazole conjugates: Microtubule-destabilizing agents

SP Shaik, VL Nayak, F Sultana, AVS Rao… - European Journal of …, 2017 - Elsevier
… Author links open overlay panel Siddiq Pasha Shaik a b , V. Lakshma Nayak a , Faria Sultana
a , AV Subba Rao a b , Anver Basha Shaik a , Korrapati Suresh Babu a , Ahmed Kamal a b …

[PDF][PDF] Social Work: A Way for Zero Hunger World

S Peta, NP Shaik - Asian Journal of Multidisciplinary Research …, 2022 - thelawbrigade.com
Social work is an art, science, profession that helps people to solve personal, and community
problems and to improve social functioning from the roots, and children in best education, …

[HTML][HTML] Oral health status and treatment needs of children with special health care needs in rural and urban areas of Hyderabad–A cross sectional study

…, KS Dwijendra, G Nagarjuna, N Shaik… - Journal of Family …, 2020 - journals.lww.com
Aim: The aim of the cross-sectional study was to ascertain the oral health status and treatment
needs of special health care need children of age group 3–16 years in rural and urban …

[HTML][HTML] Identification of a rare Exon 19 skipping mutation in ALMS1 Gene in Alström syndrome patients from two unrelated Saudi families

…, A Ahmad, KK Nasser, JY Al-Aama, NA Shaik… - Frontiers in …, 2021 - frontiersin.org
Background: Alström syndrome (AS) is a very rare childhood disorder characterized by
cardiomyopathy, progressive hearing loss and blindness. Inherited genetic variants of ALMS1 …

[HTML][HTML] Computational molecular phenotypic analysis of PTPN22 (W620R), IL6R (D358A), and TYK2 (P1104A) gene mutations of rheumatoid arthritis

NA Shaik, B Banaganapalli - Frontiers in Genetics, 2019 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic autoimmune disorder of bone joints caused by the
complex interplay between several factors like body physiology, the environment with genetic …

[HTML][HTML] Computational protein phenotype characterization of IL10RA mutations causative to early onset inflammatory bowel disease (IBD)

…, S Sadath, B Banaganapalli, K Nasser, NA Shaik - Frontiers in …, 2018 - frontiersin.org
The deleterious amino acid substitution mutations in IL-10 receptor alpha gene are most
frequently reported in several autoimmune diseases including early onset-inflammatory bowel …

[PDF][PDF] A study of identification and antifungal susceptibility pattern of Candida species isolated from various clinical specimens in a tertiary care teaching hospital …

N Shaik, U Penmetcha, RB Myneni… - Int J Curr Microbiol …, 2016 - academia.edu
The incidence of Nosocomial fungal infection has been increased due to advancement in
medical management, and change in patient profile (Fridkin SK. et al., 2006). The candida …