User profiles for Shalini Saxena

Dr. Shalini Saxena

PhD-Bits-pilani, Hyderabad campus
Verified email at indras.in
Cited by 905

Development of a new polypropylene‐based suture: plasma grafting, surface treatment, characterization, and biocompatibility studies

S Saxena, AR Ray, A Kapil… - Macromolecular …, 2011 - Wiley Online Library
Polypropylene sutures (PP) are already used in surgery. Because microbial infection leads
to complications, we developed antimicrobial PP suture by plasma‐induced graft …

Ultrasoft, highly deformable microgels

…, E Herman, JS Hyatt, P Kodlekere, Z Meng, S Saxena… - Soft Matter, 2015 - pubs.rsc.org
Microgels are colloidally stable, hydrogel microparticles that have previously been used in a
range of (soft) material applications due to their tunable mechanical and chemical properties…

[PDF][PDF] An EMG-controlled grasping system for tetraplegics

S Saxena, S Nikolic, D Popovic - Journal of rehabilitation research …, 1995 - researchgate.net
A two-channel, portable, battery operated, functional electrical stimulation (FES) system with
surface electrodes to enhance grasping in tetraplegics was developed and tested. This …

Microgel mechanics in biomaterial design

S Saxena, CE Hansen, LA Lyon - Accounts of chemical research, 2014 - ACS Publications
Conspectus The field of polymeric biomaterials has received much attention in recent years
due to its potential for enhancing the biocompatibility of systems and devices applied to drug …

Design, synthesis and biological evaluation of imidazo [2, 1-b] thiazole and benzo [d] imidazo [2, 1-b] thiazole derivatives as Mycobacterium tuberculosis pantothenate …

G Samala, PB Devi, S Saxena, N Meda… - Bioorganic & medicinal …, 2016 - Elsevier
In the present study, we have designed imidazo[2,1-b]thiazole and benzo[d]imidazo[2,1-b]thiazole
derivatives from earlier reported imidazo[1,2-a]pyridine based Mycobacterium …

Design and synthesis of novel quinoline–aminopiperidine hybrid analogues as Mycobacterium tuberculosis DNA gyraseB inhibitors

B Medapi, J Renuka, S Saxena, JP Sridevi… - Bioorganic & medicinal …, 2015 - Elsevier
Antibiotics with good therapeutic value and novel mechanism of action are becoming
increasingly important in today’s battle against bacterial resistance. One of the popular targets …

Homology modeling, docking and structure-based virtual screening for new inhibitor identification of Klebsiella pneumoniae heptosyltransferase-III

SK Panda, S Saxena, L Guruprasad - Journal of Biomolecular …, 2019 - Taylor & Francis
Abstract Klebsiella pneumoniae (K. pneumoniae) is a Gram-negative opportunistic pathogen
commonly associated with hospital-acquired infections that are often resistant even to …

Discovery of novel inhibitors of Mycobacterium tuberculosis MurG: homology modelling, structure based pharmacophore, molecular docking, and molecular dynamics …

S Saxena, M Abdullah, D Sriram… - Journal of Biomolecular …, 2018 - Taylor & Francis
MurG (Rv2153c) is a key player in the biosynthesis of the peptidoglycan layer in Mycobacterium
tuberculosis (Mtb). This work is an attempt to highlight the structural and functional …

Preparation of chitosan–polyethylene glycol coated cotton membranes for wound dressings: preparation and characterization

B Gupta, A Arora, S Saxena… - Polymers for Advanced …, 2009 - Wiley Online Library
Cotton fabric was coated with chitosan (CS) and polyethylene glycol (PEG) followed by
freeze‐drying. The influence of PEG on the physical characteristics and the surface morphology …

Structure-Guided Design of Novel Thiazolidine Inhibitors of O-Acetyl Serine Sulfhydrylase from Mycobacterium tuberculosis

O Poyraz, VU Jeankumar, S Saxena… - Journal of medicinal …, 2013 - ACS Publications
The cysteine biosynthetic pathway is absent in humans but essential in microbial pathogens,
suggesting that it provides potential targets for the development of novel antibacterial …