User profiles for Shamik Majumdar

Shamik Majumdar

National Institute of Health
Verified email at nih.gov
Cited by 727

Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1

…, ML Sandoval-Romero, S Majumdar… - Science …, 2020 - science.org
The role unconventional T cells play in protective immunity in humans is unclear. Mucosal-associated
invariant T (MAIT) cells are an unconventional T cell subset restricted to the …

WHIM syndrome: from pathogenesis towards personalized medicine and cure

LE Heusinkveld, S Majumdar, JL Gao… - Journal of clinical …, 2019 - Springer
WHIM syndrome is a rare combined primary immunodeficiency disease named by acronym
for the diagnostic tetrad of warts, hypogammaglobulinemia, infections, and myelokathexis. …

SASH3 variants cause a novel form of X-linked combined immunodeficiency with immune dysregulation

…, M Bosticardo, D Fink, S Majumdar… - Blood, The Journal …, 2021 - ashpublications.org
Sterile alpha motif (SAM) and Src homology-3 (SH3) domain-containing 3 (SASH3), also
called SH3-containing lymphocyte protein (SLY1), is a putative adaptor protein that is …

[HTML][HTML] Interferon-gamma induced cell death: regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite

…, B Saha, ES Victor, S Majumdar… - … et Biophysica Acta (BBA …, 2014 - Elsevier
Interferon-gamma (Ifnγ), a known immunomodulatory cytokine, regulates cell proliferation and
survival. In this study, the mechanisms leading to the selective susceptibility of some tumor …

Enhancing the bactericidal efficacy of nanostructured multifunctional surface using an ultrathin metal coating

A Tripathy, S Sreedharan, C Bhaskarla, S Majumdar… - Langmuir, 2017 - ACS Publications
Insects and plants exhibit bactericidal behavior through nanostructures, which leads to physical
contact killing that does not require antibiotics or chemicals. Also, certain metallic ions (…

Nitric oxide synthase 2 enhances the survival of mice during Salmonella Typhimurium infection-induced sepsis by increasing reactive oxygen species, inflammatory …

S Yadav, S Pathak, M Sarikhani, S Majumdar… - Free Radical Biology …, 2018 - Elsevier
Sepsis, a leading cause of death in intensive care units, is primarily caused due to an
exaggerated immune response. The hyperactive inflammatory response mediated by immune …

[HTML][HTML] Chemokine regulation during epidemic coronavirus infection

S Majumdar, PM Murphy - Frontiers in Pharmacology, 2021 - frontiersin.org
SARS-CoV-2 (Severe Acute Respiratory Syndrome coronavirus-2) is the third coronavirus to
emerge as a cause of severe and frequently fatal pneumonia epidemics in humans, joining …

[HTML][HTML] Toll-like receptor 2 deficiency hyperactivates the FoxO1 transcription factor and induces aging-associated cardiac dysfunction in mice

…, S Maity, AK Tamta, S Kumar, S Majumdar… - Journal of Biological …, 2018 - ASBMB
Toll-like receptors (TLRs) are a family of pattern-recognition receptors involved in innate
immunity. Previous studies have shown that TLR2 inhibition protects the heart from acute stress, …

[HTML][HTML] Adaptive immunodeficiency in WHIM syndrome

S Majumdar, PM Murphy - International journal of molecular sciences, 2018 - mdpi.com
Cysteine-X-cysteine chemokine receptor 4 (CXCR4) is a broadly expressed and multifunctional
G protein-coupled chemokine receptor critical for organogenesis, hematopoiesis, and …

Targeted photocytotoxicity by copper (II) complexes having vitamin B6 and photoactive acridine moieties

…, S Podder, S Banerjee, S Majumdar… - European Journal of …, 2016 - Elsevier
Copper(II) pyridoxal Schiff base complexes [Cu(L 1 /L 2 )(B)]ClO 4 (1–4), where HL 1 is 4-(((2-(1H-imidazol-4-yl)ethyl)imino)methyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol
(in 1 and 2), …