Real-time dynamic single-molecule protein sequencing on an integrated semiconductor device

…, J Schultz, X Shi, B Singh, N Srivastava, SF Stewman… - Science, 2022 - science.org
Studies of the proteome would benefit greatly from methods to directly sequence and digitally
quantify proteins and detect posttranslational modifications with single-molecule sensitivity…

Drosophila katanin is a microtubule depolymerase that regulates cortical-microtubule plus-end interactions and cell migration

D Zhang, KD Grode, SF Stewman… - Nature cell …, 2011 - nature.com
Regulation of microtubule dynamics at the cell cortex is important for cell motility,
morphogenesis and division. Here we show that the Drosophila katanin Dm-Kat60 functions to …

The actin-binding ERM protein Moesin binds to and stabilizes microtubules at the cell cortex

S Solinet, K Mahmud, SF Stewman… - Journal of Cell …, 2013 - rupress.org
Ezrin, Radixin, and Moesin (ERM) proteins play important roles in many cellular processes
including cell division. Recent studies have highlighted the implications of their metastatic …

[PDF][PDF] Dynamic instability from non-equilibrium structural transitions on the energy landscape of microtubule

SF Stewman, KK Tsui, A Ma - Cell systems, 2020 - cell.com
Microtubules are the backbone of the cytoskeleton and vital to numerous cellular processes.
The central dogma of microtubules is that all their functions are driven by dynamic instability…

[HTML][HTML] Mechanistic insights from a quantitative analysis of pollen tube guidance

SF Stewman, M Jones-Rhoades, P Bhimalapuram… - BMC Plant …, 2010 - Springer
Background Plant biologists have long speculated about the mechanisms that guide pollen
tubes to ovules. Although there is now evidence that ovules emit a diffusible attractant, little is …

Lattice model for self-assembly with application to the formation of cytoskeletal-like structures

SF Stewman, AR Dinner - Physical Review E, 2007 - APS
We introduce a stochastic approach for self-assembly in systems far from equilibrium. The
building blocks are represented by a lattice of discrete variables (Potts-like spins), and …

[PDF][PDF] A structural mechano-chemical model of microtubule seeded nucleation

K Tsui, SF Stewman, A Ma - Biophysical Journal, 2022 - cell.com
… 556-Pos A structural mechano-chemical model of microtubule seeded nucleation Kenneth
Tsui, Shannon F. Stewman, Ao Ma. University of Illinois at Chicago, Chicago, IL, USA. …

Mechano-chemical model for microtubule assembly: Integrating conformational dynamics of tubulins

A Ma, K Tsui, SF Stewman - Biophysical Journal, 2024 - cell.com
Microtubules are the backbone of the cytoskeleton and vital to numerous cellular processes.
All the functions of microtubules are driven by dynamic instability, but its mechanism has …

A structural mechano-chemical model for dynamic instability of microtubule

SF Stewman, A Ma - BioRxiv, 2018 - biorxiv.org
Microtubules are a major component of the cytoskeleton and vital to numerous cellular
processes. The central dogma of microtubules is that all their functions are driven by dynamic …

Dynamic instability from nonequilibrium structural transitions on the energy landscape of microtubule

A Ma, SF Stewman, K Tsui - Biophysical Journal, 2023 - cell.com
Microtubules are the backbone of the cytoskeleton and vital to numerous cellular processes.
All the functions of microtubules are driven by dynamic instability, but its mechanism has …